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Toplam kayıt 12, listelenen: 1-10
Pterjiumda Neopterin Düzeylerinin ve Kinürenin Yolağının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)
Kilicarslan B., Evaluation of Neopterin Levels and Kynurenine Pathway in Pterygium, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pterjium is an inflammatory and ...
Intracellular Generation of Ros by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity
(Oxford Univ Press, 2014)
Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder ...
Immunomodulation And Oxidative Stress In Denim Sandblasting Workers: Changes Caused By Silica Exposure
(Inst Medical Research & Occupational Health, 2013)
Workers in denim sandblasting are at a high risk of developing silicosis, an occupational lung disease caused by inhaling crystalline silica dust. The development and progress of silicosis is associated with the activation ...
Induction Of Ros, P53, P21 In Dehp- And Mehp-Exposed Lncap Cells-Protection By Selenium Compounds
(Pergamon-Elsevier Science Ltd, 2011)
This study was designed to investigate the hypothesis that the toxic effects of di(2-ethylhexyl)phthalate (DEHP), the most abundantly used plasticizer and ubiquitous environmental contaminant that cause alterations in ...
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)
This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ...
Methamidophos, Dichlorvos, O-Methoate And Diazinon Pesticides Used In Turkey Make A Covalent Bond With Butyrylcholinesterase Detected By Mass Spectrometry
(Wiley, 2010)
Organophosphorus pesticides used most commonly in Turkey include methamidophos, dichlorvos, O-methoate and diazinon. These toxic chemicals or their metabolites make a covalent bond with the active site serine of ...
Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins And Peptides Independent Of Surrounding Amino Acids
(Amer Chemical Soc, 2017)
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are irreversibly inhibited by organophosphorus pesticides through formation of a covalent bond with the active site serine. Proteins that have no active site ...
Investigating the Structural Influence of Surface Mutations on Acetylcholinesterase Inhibition by Organophosphorus Compounds and Oxime Reactivation
(Elsevier Ireland Ltd, 2010)
Organophosphates (OPs) exert their toxicity by inhibiting primarily acetylcholinesterase (AChE) and to a lesser extent butyrylcholinesterase (BChE). Binary mixtures of mammalian AChE and oximes of varying structure have ...
Evaluation Of Cytotoxicity And Oxidative Dna Damaging Effects Of Di(2-Ethylhexyl)-Phthalate (Dehp) And Mono(2-Ethylhexyl)-Phthalate (Mehp) On Ma-10 Leydig Cells And Protection By Selenium
(Academic Press Inc Elsevier Science, 2010)
Di(2-ethylhexyl)-phthalate (DEHP) is the most abundantly used phthalate derivative, inevitable environmental exposure of which is suspected to contribute to the increasing incidence of testicular dysgenesis syndrome in ...
Protective Effects of Ascorbic Acid Against the Genetic and Epigenetic Alterations Induced By 3,5-Dimethylaminophenol in Aa8 Cells
(Wiley-Blackwell, 2015)
Exposure to monocyclic aromatic alkylanilines (MAAs), namely 2,6-dimethylaniline (2,6-DMA), 3,5-dimethylaniline (3,5-DMA) and 3-ethylaniline (3-EA), was significantly and independently associated with bladder cancer ...