Ara
Toplam kayıt 30, listelenen: 21-30
Siklofosfamid ile İndüklenmiş Fare Sistit Modelinde Agonist ile İndüklenen Kasılma Yanıtlarındaki Bozulmada Hidrojen Sülfür ile Reaktif Oksijen Türevlerinin Rolü ve Etkileşimi
(Sağlık Bilimleri Enstitüsü, 2023)
Interstitial cystitis is a syndrome characterized by sensory and motor dysfunction of the lower urinary tract. Hydrogen sulfide is an endogenously produced gasotransmitter and is responsible for regulating many functions. ...
Deneysel Alerjik Astım Modelinde Mitokondri Hedefli Hidrojen Sülfür Donörü AP39 Tedavisinin Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)
In this thesis, the effect of AP39, which is a mitochondria targeted slow releasing hydrogen sulfide (H2S) donor, were investigated in a mouse model of ovalbumin (OVA)-induced allergic asthma. In this model, experimental ...
Eroinin glutatyon metabolizması üzerindeki etkisinin metabolomik düzeyde araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)
Heroin is a substance that is a synthetic opioid derivative with a high
addictive potential. Serious toxic effects may occur due to heroin use. Although many
different mechanisms are effective in the emergence of these ...
Betametazon sodyum fosfat ve betametazon dipropiyonat’ın bozunma ürünlerinin varlığında yüksek basınçlı sıvı kromatografisi ile aynı anda analizleri
(Sağlık Bilimleri Enstitüsü, 2023-01)
Betamethasone Sodium Phosphate and Betamethasone Dipropionate active ingredients and preservatives were analyzed in the presence of degradation products by HPLC method.
Melazma tedavisinde yeni yaklaşımlar ve olası toksik etkilerinin in vitro olarak değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)
Melasma is a chronic, acquired disease
that results in the accumulation of brown or gray-brown melanin pigment in the epidermis layer
and/or dermis layer, especially in areas where the body is more exposed to sunlight, ...
Alkol Esteri Yapısındaki Yeni Azol Türevlerinin Sentezi, Biyolojik Aktiviteleri, Moleküler Modelleme Çalışmaları ve Yapı-Etki İlişkileri
(Sağlık Bilimleri Enstitüsü, 2023)
In this study, various carboxylic acid esters of 1-aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanol was synthesized in order to discovery new organic compounds with antimicrobial and anticholinesterase effects; ...
Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation
(Sağlık Bilimleri Enstitüsü, 2023-03-14)
Development of Anticancer Drug Loaded Nanoparticle and In-Vitro Evaluation, Hacettepe University Graduate School of Health Sciences Pharmaceutical Technology Master of Science Thesis, Ankara 2023. Colorectal cancer is the ...
Investigation of Possible Protective Effects of Certain Xenobiotics on Aluminum Toxicity in SH-SY5Y Cell Line
(Sağlık Bilimleri Enstitüsü, 2023-11-16)
Aluminum, a neurotoxic metal, is widely present in our daily lives, exposing us extensively. Aluminum exposure is a potential Alzheimer's risk factor, with no cure yet. Researchers are actively seeking new treatments or ...
Alzheimer Hastalığının in vitro Modellerinde Herpes Simpleks Proteinlerinin Kompleman Sistem, Sitokinler ve Epigenetik Değişiklikler Üzerindeki Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)
Alzheimer's disease (AD) is characterized by decline in cognitive functions and dementia. Most cases are sporadic. However, some of these cases may develop from genetic or epigenetic origins. Additionally, it has been ...
Farmasötik Ürünlerde Tüketilebilirlik Çalışmalarına Analitik Yaklaşımlar
(Sağlık Bilimleri Enstitüsü, 2023-12-21)
Ignoring the effects of extractable substances not only creates great difficulties for drug manufacturers and regulations, but also changes the safety of the drug due to the dangers that impurities may cause. The suitability ...