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The Effect Of Effort Test On The Levels Of Ischemia Modified Albumin, 7-Ketocholesterol And Cholestan-3Β , 5Α , 6Β -Triol And Their Role In The Diagnosis Of Coronary Artery Disease 

Keles, Muhammed Emin; Samadi, Afshin; Isikhan, Selen Yilmaz; Sener, Yusuf Ziya; Sezgin, Ali; Keles, Emine; Lay, Incilay; Canpolat, Uğur (2019)
Background Oxysterols have been shown to play a role in plaque formation while ischemia modified albumin (IMA) is widely accepted as an acute marker for ischemia. The effort test is one of the methods used to identify the ...

Kojic Acid Derivatives As Potential Anticancer Agents: Synthesis And Cytotoxic Evaluation On A375 Human Malignant Melanoma Cells 

Karakaya, Gulsah; Ercan, Ayse; Oncul, Selin; Aytemir, Mutlu Dilsiz (2019)
Malignant melanoma is a serious type of skin cancer with high mortality rates, arising from melanocytic cells responsible for the pigmentation of the skin. Besides, the excessive accumulation of melanin pigment can lead ...

Molecularly Imprinted Polymer Based Sensors For Medical Applications 

Saylan, Yeşeren; Akgönüllü, Semra; Yavuz, Handan; Ünal, Serhat; Denizli, Adil (2019)
Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In ...

Molecularly Imprinted Biomimetic Surface Plasmon Resonance Sensor For Hormone Detection 

Turkoglu, Emir Alper; Bakhshpour, Monireh; Denizli, Adil (2019)
In this study, 17 beta-estradiol (E2) was performed by surface plasmon resonance (SPR) based on molecularly imprinted technique. In the first, SPR sensor was prepared by the formation of E2 imprinted poly(2-hydroxyetyl ...

Long-Term Effects Of Early-Life Antibiotic Exposure On Resistance To Subsequent Bacterial Infection 

Roubaud-Baudron, Claire; Ruiz, Victoria E.; Swan, Alexander M.; Vallance, Bruce A.; Ozkul, Ceren; Pei, Zhiheng; Li, Jackie; Battaglia, Thomas W.; Perez-Perez, Guillermo I.; Blaser, Martin J. (2019)
The gastrointestinal microbiota protects hosts from enteric infections; while antibiotics, by altering the microbiota, may diminish this protection. We show that after early-life exposure to antibiotics host susceptibility ...

Islamic Fasting Leads To An Increased Abundance Of Akkermansia Muciniphila And Bacteroides Fragilis Group: A Preliminary Study On Intermittent Fasting 

Özkul, Ceren; Yalınay, Meltem; Karakan, Tarkan (2019)
Background/Aims It has been largely accepted that dietary habits affect intestinal microbiota composition. In this pilot study, we hypothesized that time-restricted feeding, which can be regarded as a type of intermittent ...

Neurotoxic Effects Of Bisphenol A On Sh-Sy5Y Neuroblastoma Cells Via Nitric Oxide 

Ayazgok, Beyza; Tuylu Kucukkilinc, Tuba (2019)
Bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl)propane)polycarbonate is an industrial component frequently used as an additive in the construction of epoxy resin and other non-polymer plastics. In this study cytotoxicity of low ...

Low-Dose Bisphenol A Induces Ripk1-Mediated Necroptosis In Sh-Sy5Y Cells: Effects On Tnf-Alpha And Acetylcholinesterase 

Ayazgoek, Beyza; Kucukkilinc, Tuba Tueylue (2019)
Bisphenol A (BPA) is an endocrine disruptor chemical, which is commonly used in everyday products. Adverse effects of its exposure are reported even at picomolar doses. Effects of picomolar and nanomolar concentrations of ...

Molecularly Imprinted Polymer-Based Microfluidic Systems For Point-Of-Care Applications 

Saylan, Yeşeren; Denizli, Adil (2019)
Fast progress has been witnessed in the field of microfluidic systems and allowed outstanding approaches to portable, disposable, low-cost, and easy-to-operate platforms especially for monitoring health status and point-of-care ...

Analysis Of The Antiproliferative Effect Of Ankaferd Hemostat On Caco-2 Colon Cancer Cells Via Lc/Ms Shotgun Proteomics Approach 

Koçak, Engin; Çelebier, Mustafa; Haznedaroglu, Ibrahim C.; Altınöz, Sacide (2019)
Ankaferd hemostat (ABS), a traditional herbal extract, is a hemostatic agent used for wound healing and bleeding treatment. A standardized form of plants contains many biomolecules. In recent years, previous studies have ...
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