• 18Th European Symposium On Radiopharmacy And Radiopharmaceuticals 

      Radchenko, V.; Engle, J. W.; Roy, C.; Griswold, J.; Nortier, M. F.; Birnbaum, E. R.; Brugh, M.; Mirzadeh, S.; John, K. D.; Fassbender, M. E.; Zhai, Chuangyan; Franssen, Gerben M.; Petrik, Milos; Laverman, Peter; Decristoforo, Clemens; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Brigitte, Guérin; Summer, D.; Kroess, A.; Rangger, C.; Haas, H.; Laverman, P.; Gerben, F.; von Guggenberg, E.; Decristoforo, C.; Bolzati, Cristina; Salvarese, Nicola; Refosco, Fiorenzo; Meléndez-Alafort, Laura; Carpanese, Debora; Rosato, Antonio; Saviano, Michele; Del Gatto, Annarita; Comegna, Daniela; Zaccaro, Laura; Billaud, Emilie; Ahamed, Muneer; Cleeren, Frederik; Shahbazali, Elnaz; Noël, Tim; Hessel, Volker; Verbruggen, Alfons; Bormans, Guy; Cleeren, F.; Lecina, J.; Koole, M.; Verbruggen, A.; Bormans, G.; Lugatoa, B.; Stucchia, S.; Turollaa, E. A.; Giulianoa, L.; Toddea, S.; Ferraboschib, P.; Klok, R. P.; Mooijer, M. P. J.; Hendrikse, N. H.; Windhorst, A. D.; Collet, C.; Petry, N.; Chrétien, F.; Karcher, G.; Pellegrini-Moïse, N.; Lamandé-Langle, S.; Pfaff, Sarah; Philippe, Cecile; Mitterhauser, Markus; Hacker, Marcus; Wadsak, Wolfgang; Guérard, François; Lee, Yong-Sok; Gouard, Sébastien; Baidoo, Kwamena; Alliot, Cyrille; Chérel, Michel; Brechbiel, Martin W.; Gestin, Jean-François; Lam, K.; Chan, C.; Reilly, R. M.; Paillas, Salomé; Marshall, John; Pouget, Jean-Pierre; Sosabowski, Jane; Briard, Emmanuelle; Auberson, Yves P.; Reilly, John; Healy, Mark; Sykes, David; Paulus, Andreas; Lichtenbelt, Wouter van Marken; Mottaghy, Felix; Bauwens, Matthias; Baranski, Ann-Christin; Schäfer, Martin; Bauder-Wüst, Ulrike; Haberkorn, Uwe; Eder, Matthias; Kopka, Klaus; Chaussard, M.; Hosten, B.; Vignal, N.; Tsoupko-Sitnikov, V.; Hernio, N.; Hontonnou, F.; Merlet, P.; Poyet, J. L.; Sarda-Mantel, L.; Rizzo-Padoin, N.; Cardinale, J.; Schäfer, M.; Benešová, M.; Bauder-Wüst, U.; Seibert, O.; Giesel, F.; Haberkorn, U.; Eder, M.; Kopka, K.; Nematallah, Mansour; Michel, Paquette; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Roger, Lecomte; Brigitte, Guérin; Fernandez-Maza, L.; Rivera-Marrero, S.; Capote, A. Prats; Parrado-Gallego, A.; Fernandez-Gomez, I.; Balcerzyk, M.; Sablon-Carrazana, M.; Perera-Pintado, A.; Merceron-Martinez, D.; Acosta-Medina, E.; Rodriguez-Tanty, C.; Attili, Bala; Ahamed, Muneer; Bormans, Guy; Philippe, C.; Zeilinger, M.; Scherer, T.; Fürnsinn, C.; Dumanic, M.; Wadsak, W.; Hacker, M.; Mitterhauser, M.; Janssen, B.; Vugts, D. J.; Molenaar, G.T. T.; Funke, U.; Kruijer, P. S.; Dollé, F.; Bormans, G.; Lammertsma, A. A.; Windhorst, A. D.; Vermeulen, Koen; Ahamed, Muneer; Schnekenburger, Michael; Froeyen, Mathy; Olberg, Dag Erlend; Diederich, Marc; Bormansa, Guy; Raaphorst, R. M.; Luurtsema, G.; Lammertsma, A. A.; Elsinga, P. H.; Windhorst, A D.; Rotteveel, Lonneke; Funke, Uta; ten Dijke, Peter; Bogaard, Harm Jan; Lammertsma, Adriaan A.; Windhorst, Albert D.; Song, Lei; Able, Sarah; Falzone, Nadia; Kersemans, Veerle; Vallis, Katherine; Carta, Davide; Salvarese, Nicola; Sihver, Wiebke; Gao, Feng; Pietzsch, Hans Jürgen; Biondi, Barbara; Ruzza, Paolo; Refosco, Fiorenzo; Bolzati, Cristina; Haubner, Roland; Finkensted, Armin; Stegmair, Armin; Rangger, Christine; Decristoforo, Clemens; Zoller, Heinz; Virgolini, Irene J.; Pooters, Ivo; Lotz, Maartje; Wierts, Roel; Mottaghy, Felix; Bauwens, Matthias; Forsback, Sarita; Jörgen, Bergman; Riikka, Kivelä; Karageorgou, M.; Radović, M.; Tsoukalas, C.; Antic, B.; Gazouli, M.; Paravatou-Petsotas, M.; Xanthopouls, S.; Calamiotou, M.; Stamopoulos, D.; Vranješ-Durić, S.; Bouziotis, P.; Lunev, A. S.; Larenkov, A. A.; Petrosova, K. A.; Klementyeva, O. E.; Kodina, G. E.; Kvernenes, O. H.; Adamsen, T. C. H.; Martin, René; Weidlich, Sebastian; Zerges, Anna-Maria; Gameiro, Cristiana; Lazarova, Neva; Müllera, Marco; Luurtsema, Gert; de Vries, Michèl; Ghyoot, Michel; van der Woude, Gina; Zijlma, Rolf; Dierckx, Rudi; Boersma, Hendrikus H.; Elsinga, Philip H.; Lambrecht, Fatma Yurt; Er, Ozge; Ince, Mine; Avci, Cıgır Biray; Gunduz, Cumhur; Sarı, Fatma Aslihan; Ocakoglu, Kasim; Er, Ozge; Ersoz, Onur Alp; Lambrecht, Fatma Yurt; Ince, Mine; Kayabasi, Cagla; Gunduz, Cumhur; Kniess, Torsten; Meister, Sebastian; Fischer, Steffen; Steinbach, Jörg; Ashfaq, Rabia; Iqbal, Saeed; ullah Khan, Irfan; Iglesias-Jerez, R.; Martín-Banderas, L.; Perera-Pintado, A.; Borrego-Dorado, I.; Farinha-Antunes, Ines; Kwizera, Chantal; Lacivita, Enza; Lucente, Ermelinda; Niso, Mauro; De Giorgio, Paola; Perrone, Roberto; Colabufo, Nicola A.; Elsinga, Philip H.; Leopoldo, Marcello; Vaulina, V. V.; Fedorova, O. S.; Orlovskaja, V. V.; Chen, ?�. L.; Li, G. Y.; Meng, F. C.; Liu, R. S.; Wang, H. E.; Krasikova, R. N.; Meléndez-Alafort, Laura; Abozeid, Mohamed; Ferro-Flores, Guillermina; Negri, Anna; Bello, Michele; Uzunov, Nikolay; Paiusco, Martha; Esposito, Juan; Rosato, Antonio; Meléndez-Alafort, Laura; Bolzati, Cristina; Ferro-Flores, Guillermina; Salvarese, Nicola; Carpanese, Debora; Abozeid, Mohamed; Rosato, Antonio; Uzunov, Nikolay; Palmieri, L.; Verbrugghen, T.; Glassner, M.; Hoogenboom, R.; Staelens, S.; Wyffels, L.; Orlovskaja, V. V.; Kuznetsova, O. F.; Fedorova, O. S.; Maleev, V. I.; Belokon, Yu. N.; Geolchanyan, A.; Saghyan, A. S.; Mu, L.; Schibli, R.; Ametamey, S. M.; Krasikova, R. N.; Revunov, Evgeny; Malmquist, Jonas; Johnström, Peter; Van Valkenburgh, Juno; Steele, Dalton; Halldin, Christer; Schou, Magnus; Osati, Samira; Paquette, Michel; Beaudoin, Simon; Ali, Hasrat; Guerin, Brigitte; Leyton, Jeffrey V.; van Lier, Johan E.; Di Iorio, V; Iori, M.; Donati, C.; Lanzetta, V.; Capponi, P. C.; Rubagotti, S.; Dreger, T.; Kunkel, F.; Asti, M.; Zhai, Chuangyan; Rangger, Christine; Summer, Dominik; Haas, Hubertus; Decristoforo, Clemens; Kijprayoon, Suphansa; Ruangma, Ananya; Ngokpol, Suthatip; Tuamputsha, Samart; Filp, Ulrike; Pees, Anna; Taddei, Carlotta; Pekošak, Aleksandra; Gee, Antony D.; Poot, Alex J.; Windhorst, Albert D.; Gunay, Mine Silindir; Ozer, A. Yekta; Erdogan, Suna; Baysal, Ipek; Guilloteau, Denis; Chalon, Sylvie; Galli, Filippo; Artico, Marco; Taurone, Samanta; Bianchi, Enrica; Weintraub, Bruce D.; Skudlinski, Mariusz; Signore, Alberto; Lepareur, Nicolas; Noiret, Nicolas; Hindré, François; Lacœuille, Franck; Benoist, Eric; Garin, Etienne; Trejo-Ballado, F.; Zamora-Romo, E.; Manrique-Arias, J. C.; Gama-Romero, H M; Contreras-Castañon, G.; Tecuapetla-Chantes, R. G.; Avila-Rodriguez, M. A.; Kvaternik, H.; Hausberger, D.; Zink, C.; Rumpf, B.; Aigner, R. M.; Kvaternik, H.; Hausberger, D.; Rumpf, B.; Aigner, R. M.; Janković, Drina; Lakić, Mladen; Savić, Aleksandar; Ristić, Slavica; Nikolić, Nadežda; Vukadinović, Aleksandar; Sabo, Tibor J.; Vranješ-Đurić, Sanja; Vranješ-Đurić, S.; Radović, M.; Janković, D.; Nikolić, N.; Goya, G. F.; Calatayud, P.; Spasojević, V.; Antić, B.; Goblet, David; Gameiro, Cristiana; Lazarova, Neva; Gameiro, Cristiana; Oxley, Ian; Abrunhosa, Antero; Kramer, Vasko; Vosjan, Maria; Spaans, Arnold; Vats, Kusum; Satpati, Drishty; Sarma, Haladhar D.; Banerjee, Sharmila; Wojdowska, W.; Pawlak, D. W.; Parus, L. J.; Garnuszek, P.; Mikołajczak, R.; Pijarowska-Kruszyna, J.; Jaron, A.; Kachniarz, A.; Malkowski, B.; Garnuszek, P.; Mikolajczak, R.; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Eveliina, Arponen; Semi, Helin; Timo, Saarinen; Simo, Vauhkala; Esa, Kokkomäki; Pertti, Lehikoinen; De Simone, Mariarosaria; Pascali, Giancarlo; Carzoli, Ludovica; Quaglierini, Mauro; Telleschi, Mauro; Salvadori, Piero A.; Lam, Phoebe; Aistleitner, Martina; Eichinger, Reinhard; Artner, Christoph; Nakka, Surendra; MC, Hemantha Kumara; Al-Qahtani, Mohammed; Al-Qahtani, Mohammed; Al-Malki, Yousif; Mambilima, N.; Rubow, S. M.; Berroterán-Infante, N.; Hacker, M.; Mitterhauser, M.; Wadsak, W.; Funke, Uta; Cleeren, Frederik; Lecina, Joan; Gallardo, Rodrigo; Verbruggen, Alfons M.; Bormans, Guy; Ramos-Membrive, Rocío; Brotons, Ana; Quincoces, Gemma; Inchaurraga, Laura; de Redín, Inés Luis; Morán, Verónica; García-García, Berta; Irache, Juan Manuel; Peñuelas, Iván; Trabelsi, M.; Cooper, M. S.; Abella, Alejandra; Fuente, Teodomiro; Montellano, Antonio Jesús; Martínez, Teresa; Rabadan, Ruben; Meseguer-Olmo, Luis; Lehtiniemi, P.; Yim, C.; Mikkola, K.; Nuutila, P.; Solin, O.; von Guggenberg, E.; Rangger, C.; Mair, C.; Balogh, L.; Pöstényi, Z.; Pawlak, D.; Mikołajczak, R.; Socan, A.; Peitl, P. Kolenc; Krošelj, M.; Rangger, C.; Decristoforo, C.; Collet, C.; Remy, S.; Didier, R.; Vergote, T.; Karcher, G.; Véran, N.; Pawlak, D.; Maurin, M.; Garnuszek, P.; Karczmarczyk, U.; Mikołajczak, R.; Fredericia, Pil; Severin, Gregory; Groesser, Torsten; Köster, Ulli; Jensen, Mikael; Leonte, R.; Puicea, F. D.; Raicu, A.; Min, E. A.; Serban, R.; Manda, G.; Niculae, D.; Zerna, Marion; Schieferstein, Hanno; Müller, Andre; Berndt, Mathias; Yim, Cheng-Bin; Mikkola, Kirsi; Nuutila, Pirjo; Solin, Olof; Seifert, D.; Ráliš, J.; Lebeda, O.; Selivanova, Svetlana V.; Senta, Helena; Lavallée, Éric; Caouette, Lyne; Turcotte, Éric; Lecomte, Roger; Kochovska, Marina Zdraveska; Ivanovska, Emilija Janjevik; Jokic, Vesna Spasic; Ackova, Darinka Gjorgieva; Smilkov, Katarina; Makreski, Petre; Stafilov, Trajče; Janevik-Ivanovska, Emilija; Alemu, Aschalew; Muchira, Joel Munene; Wanjeh, David Mwanza; Janevik-Ivanovska, Emilija; Janevik-Ivanovska, Emilija; Zdravev, Zoran; Bhonsle, Uday; Alberto, Osso Júnior João; Duatti, Adriano; Angelovska, Bistra; Stojanovska, Zdenka; Sarafinovska, Zorica Arsova; Bosnakovski, Darko; Gorgieva-Ackova, Darinka; Smilkov, Katarina; Drakalska, Elena; Venkatesh, Meera; Gulaboski, Rubin; Colin, Didier J.; Inkster, James A. H.; Germain, Stéphane; Seimbille, Yann (2016)
      OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ...
    • A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application 

      Eroglu, Hakan; Nemutlu, Emirhan; Turkoglu, Omer Faruk; Nacar, Osman; Bodur, Ebru; Sargon, Mustafa Fevzi; Beskonakli, Etem; Oner, Levent (Pharmaceutical Soc Japan, 2010)
      Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ...
    • An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery 

      Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen (2012)
      Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ...
    • Characterization Of Protein And Peptide Binding To Nanogels Formed By Differently Charged Chitosan Derivatives 

      Zubareva, Anastasia; Ilyina, Alla; Prokhorov, Aleksander; Kurek, Denis; Efremov, Mikhail; Varlamov, Valery; Senel, Sevda; Ignatyev, Pavel; Svirshchevskaya, ?�lena (2013)
      Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both for Chi derivatization and for particle ...
    • Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets 

      Ozturk, Naile; Kaynak, Mustafa Sinan; Sahin, Selma (Dissolution Technologies, Inc, 2015)
      The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ...
    • Comparison Of Intestinal Permeability Of Nebivolol Hydrochloride Loaded Solid Lipid Nanoparticles With Commercial Nebivolol Tablet 

      Gökçe, E.H; Kaynak, M.S; Yurdasiper, A; Üstündağ-Okur, N; Şahin, S. (2018)
    • Dendrimeric Systems And Their Applications In Ocular Drug Delivery 

      Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen (2013)
      Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ...
    • Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe 

      Gülsün, Tugba; Gürsoy, Reyhan Neslihan; Öner, Levent (Pharmaceutical Soc Japan, 2011)
      Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ...
    • Determination Of N-Acetylcysteine In The Presence Of Ciprofloxacin Or Levofloxacin In Microparticulate Dry Powder Inhalers 

      Akdag, Yagmur; Sahin, Selma; Nemutlu, Emirhan; Oner, Levent (2019)
      A fast and easy method was validated for simultaneous determination of ciprofloxacin hydrochloride mono hydrate (CP), levofloxacin hemihydrate (LV), and N-acetylcysteine (NAC) in samples. The analysis was performed on a ...
    • Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method 

      Kaynak, Mustafa Sinan; Büyüktuncel, Ebru; Çağlar, Hatice; Şahin, Selma (Pharmacotherapy Group, 2015)
      Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ...
    • Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System 

      Faraj, Jabar A.; Dorati, Rossella; Schoubben, Aurelie; Worthen, David; Selmin, Francesca; Capan, Yilmaz; Leung, Kai; DeLuca, Patrick P. (Springer, 2007)
      The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ...
    • Development Of Dry Powder Inhaler Formulations For Drug Delivery Systems 

      Akdag, Yagmur (2019)
      Oral or parenteral administration of drugs to treat lung diseases is met with several challenges, including delivery of the active substance in insufficient amounts, inability to produce the desired effect at the target ...
    • Development Of Novel Self-Assembled Polymeric Micelles From Partially Hydrolysed Poly(2-Ethyl-2-Oxazoline)-Co-Pei-B-Pcl Block Copolymer As Non-Viral Vectors For Plasmid Dna In Vitro Transfection 

      Kara, Aslı; Öztürk, Naile; Esendağlı, Güneş; Özköse, Umut Uğur; Gülyüz, Sevgi; Yılmaz, Özgür; Telci, Dilek; Bozkir, Asuman; Vural, Imran (Taylor & Francis Ltd, 2018)
      A new efficient, non-viral gene delivery cationic polymeric micellar system was developed by partial hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOx) with two different hydrolysis percentages of PEtOx (30% and 60%) to reduce ...
    • Development of Polycationic Amphiphilic Cyclodextrin Nanoparticles for Anticancer Drug Delivery 

      Varan, Gamze; Benito, Juan M; Mellet, Carmen Ortiz; Bilensoy, Erem (2017)
      Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon ...
    • Drug Delivery Systems for Imaging And Therapy of Parkinson'S Disease 

      Günay, Mine Silindir; Özer, A. Yekta; Chalon, Sylvie (2016)
      Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson’s disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain ...
    • Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery 

      Elicora, Aykut; Liman, Serife T.; Yegin, Betul Arica; Akgul, Asli G.; Eroglu, Hakan; Yildiz, Kursat; Topcu, Salih; Ozer, Cuneyt (Daedalus Enterprises Inc, 2014)
      BACKGROUND: Tracheal stenosis constitutes one of the most frequently seen problems in thoracic surgery. Although many treatment modalities to prevent fibroblast proliferation, angiogenesis, or inflammation that causes ...
    • Effect Of Particle Size And Surfactant On The Solubility, Permeability And Dissolution Characteristics Of Deferasirox 

      Gulsun, Tugba; Akdag, Yagmur; Izat, Nihan; Oner, Levent; Sahin, Selma (2019)
      Deferasirox is an oral iron chelator used for the treatment of chronic iron overload in blood transfusions. Deferasirox is a BCS Class II drug with low solubility and high permeability. In the formulation development stage ...
    • Effect of Topically Applied Sildenafil Citrate on Wound Healing: Experimental Study 

      Gürsoy, Koray; Oruç, Melike; Kankaya, Yüksel; Ulusoy, M. Gürhan; Koçer, Uğur; Kankaya, Duygu; Gürsoy, R. Neslihan; Çevik, Özge; Ogus, Elmas; Fidanci, Vildan (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2014)
      Wound healing is a complex process that necessitates organization of different cell types and several signalling molecules. The aim of this study is to evaluate the effect of different concentrations of sildenafil citrate, ...
    • Effects Of Transforming Growth Factor-Beta-1 Neutralizing Antibody And Transforming Growth Factor-Beta-3 On The Development Of Tracheal Stenosis 

      Elicora, Aykut; Ozcelikay, Goksu; Sezer, Huzeyin Fatih; Liman, Serife Tuba; Yildiz, Kursat; Topcu, Salih; Arica, Betul (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2017)
      Background: This study aims to evaluate the effects of transforming growth factor-beta 3 and neutralizing antibody of transforming growth factor-beta 1 containing polymeric polycaprolactone film formulations on prevention ...
    • Estimation Of Aqueous Distributional Spaces In The Dual Perfused Rat Liver 

      Sahin, S; Rowland, M (Cambridge Univ Press, 2000)
      1. The aim of this study was to estimate the aqueous distributional spaces of the liver as a function of the route of input: portal vein (PV) versus hepatic artery (HA). 2. Studies were performed in the in situ single (PV) ...