Konu "Sitotoksisite" için Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu listeleme
Toplam kayıt 13, listelenen: 1-13
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Bisfenol Türevlerinin Oksidatif Stres Parametreleri Üzerine Etkilerinin HepG2 Hücrelerinde Karşılaştırmalı Olarak Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenols belong to a chemical group known as diphenylmethanes and widely used in the production of polycarbonate plastics, as basic chemicals in the resin coating of food and beverage tins. These substances are suggested ... -
Bitkisel Kaynaklı Fenolik Yapıdaki Bileşiklerin Olası Sitotoksik ve Genotoksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2014)Free oxygen radicals react with genetic material such as DNA, RNA and other cell macromolecules and the cause oxidative damage. There is a worldwide increasing interest about antioxidant compounds which could delay or ... -
Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ... -
Endokrı̇n Bozucu Kı̇myasal Maddelere Kombı̇ne Maruzı̇yetı̇n Etkı̇lerinin Hepg2 Hücre Hattında Değerlendı̇rilmesı̇
(Sağlık Bilimleri Enstitüsü, 2018-04-24)Endocrine disruptors are synthetic or natural substances that disrupt the normal functioning of the body by mimicking or blocking hormones. They are suggested to affect many basic periods and characteristics like growth, ... -
Evaluation of Cytotoxic and Genotoxic Properties of Sinapic Acid
(Sağlık Bilimleri Enstitüsü, 2014)Phenolic compounds, one of the most widely occurring groups of phytochemicals, play an important role in the growth and reproduction of plants, providing protection against pathogens and predators, also contributing towards ... -
Evaluation of Cytotoxicity and Genotoxicity of Eugenol in Lymphocytes
(Sağlık Bilimleri Enstitüsü, 2014)Eugenol is a volatile phenolic constituent of clove essential oil obtained from Eugenia Caryophyllata buds and leaves. It is a functional ingredient in numerous products. It has been used in the pharmaceutical and cosmetics ... -
Halk İlacı Olarak Kullanılan Peganum harmala L. (Üzerlik) Tohumları Üzerinde İlaç Hammaddesi Yönünden Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2022)Peganum harmala L., which is the only species representing the genus Peganum in Turkey, is known as “üzerlik” and is widely used as folk medicine. It is known that pharmacological studies performed on the plant support ... -
Inula Fragılıs Boıss. & Hausskn. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2023)Uzun, K., Pharmacognosical studies on Inula fragilis Boiss. & Hausskn., Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, PhD Thesis, Ankara, 2023. Inula L. (Asteraceae) species are rich in ... -
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Metformin is a biguanide derivative widely used in the treatment of diabetes mellitus. Recent studies have shown the anticancer properties of metformin. The possible mechanisms of anticancer effects of metformin have ... -
Piknogenol ve Kurkuminin Çeşitli Kanser Hücre Hatlarında Sisplatin Sitotoksisitesine Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-01-13)Pycnogenol from Pinus pinaster and curcumin from Curcuma longa L., are poliphenolic compounds and commonly used in many diseases traditionally due to their high antioxidant properties. Cisplatin, an antineoplastic agent, ... -
Pitavastatin Sitotoksisitesinin Serviks Kanser Hücre (Hela) Hattında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Cervical cancer which is one of the most common cancer types in women throughout the world. Investigation of possible and alternative treatment methods of cervical cancer will lead to the discovery of new effective treatment ... -
Serviks Kanserinde Timokinon ve Etoposid Kombinasyonunun Hücre Canlılığı Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2022). Cervical cancer is the second most common type of cancer in women, after breast cancer, that causes the death of a woman every two minutes in the world. Major treatment options include surgery, radiotherapy, and ... -
Yeni Hekzahidrokinolin Türevlerinin Sentezi, Karakterizasyonu, Sitotoksisite, İntrasellüler Ros Üretimi ve Enflamasyon Mediyatörlerine İnhibitör Etkilerinin Saptanması
(Sağlık Bilimleri Enstitüsü, 2023-07-14)In this study, 15 compounds with the general structure of hexahydroquinoline-3-carboxylate, a condensed derivative of 1,4-DHP, which are expected to show inhibitory activity on inflammatory mediators, were synthesized. The ...