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Toplam kayıt 135, listelenen: 1-10
The Effects of Di(2-Ethylhexyl)Phthalate on Rat Liver in Relation to Selenium Status
(Wiley-Blackwell, 2014)
This study was performed to determine the hepatotoxicity of di(2-ethylhexyl)phthalate (DEHP) in relation to selenium status. In 3-week-old Sprague-Dawley rats, selenium deficiency was induced by a 0.05 selenium mg/kg. A ...
Intracellular Generation of Ros by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity
(Oxford Univ Press, 2014)
Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder ...
Investigation of 1377C/T Polymorphism of the Toll-Like Receptor 3 Among Patients with Chronic Hepatitis B
(Canadian Science Publishing, Nrc Research Press, 2016)
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis ...
Infliximab Alleviates The Mortality, Mesenteric Hypoperfusion, Aortic Dysfunction, And Multiple Organ Damage In Septic Rats
(Canadian Science Publishing, Nrc Research Press, 2017)
Tumor necrosis factor-alpha (TNF-alpha) is a pivotal mediator that triggers inflammatory process, oxidative stress, and multiple organ injury in sepsis. We investigated the effects of infliximab on survival, mesenteric ...
Inhibitory Effect Of The Methanolic Extract Of Verbascum Latisepalum Hub.-Mor. On Endothelium-Dependent Relaxation In Rat Thoracic Aorta
(Walter De Gruyter Gmbh, 2014)
The leaves and flowers of Verbascum species are used to treat respiratory disorders, haemorrhoids, rheumatic pain, and wounds as well as for the treatment of eczema and other types of inflammatory skin conditions in ...
Isolation And Structure Elucidation Of Uncommon Secondary Metabolites From Cistus Salviifolius L.
(Acg Publications, 2015)
To our knowledge this is the first report on the isolation of a flavonoid glycoside: quercetin 3-O-alpha-arabinopyranoside (5), two phenylbutanon glycosides: 4-(4'-O-[6''-O-galloyl-beta-galactopyranosyl]-3'-hydroxyphenyl ...
Folate, Neopterin And Kynurenine Pathway In Patients With Statin Therapy
(Walter De Gruyter Gmbh, 2016)
Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes. ...
Flavonoids From Sideritis Species: Human Monoamine Oxidase (Hmao) Inhibitory Activities, Molecular Docking Studies And Crystal Structure Of Xanthomicrol
(2015)
The inhibitory effects of flavonoids on monoamine oxidases (MAOs) have attracted great interest since alterations in monoaminergic transmission are reported to be related to neurodegenerative diseases such as Parkinson’s ...
Gpcr Modulation Of Thieno[2,3-B]Pyridine Anti-Proliferative Agents
(2017)
A panel of docking scaffolds was developed for the known molecular targets of the anticancer agents, thieno[2,3-b]pyridines, in order to glean insight into their mechanism of action. The reported targets are the ...