Bölüm "Farmasötik Toksikoloji" Eczacılık Meslek Bilimleri Bölümü Makale Koleksiyonu için listeleme
Toplam kayıt 57, listelenen: 21-40
-
Evaluation Of Dihydropteridine Reductase Activities In Patients With Kidney Failure
(Walter De Gruyter Gmbh, 2013)End-stage renal disease (ESRD) is the inability of the kidneys to remove waste products from the blood. The most important factors causing ESRD that require hemodialysis are diabetes and hypertension. There are limited ... -
Evaluation of Oxidative and Antioxidative Parameters in Pediatric Hematopoietic SCT Patients
(Springer Nature, 2012)Conditioning regimens preceding hematopoietic SCT (HSCT) usually consist of high-dose chemotherapy. Chemotherapy and radiation therapy are associated with increased formation of free radicals and depletion of critical ... -
Flavonoid Derivatives From The Aerial Parts Of Trifolium Trichocephalum M. Bieb. And Their Antioxidant And Cytotoxic Activity
(Acg Publications, 2017)Trifolium L. species with a rich isoflavone content have been used as expectorant, analgesic, antiseptic, tonic, and wound- healer in folk medicine. The aim of the study is to evaluate pharmacological properties of the ... -
Folate, Neopterin And Kynurenine Pathway In Patients With Statin Therapy
(Walter De Gruyter Gmbh, 2016)Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes. ... -
Hepatoprotective And Antioxidant Effects Of Lycopene In Acute Cholestasis
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: Lycopene, which is suggested to be a potent antioxidant, may play a protective role in diseases related to oxidative stress. In order to understand the effects of lycopene in the pathogenesis of cholestasis, ... -
Hplc Method For Naproxen Determination In Human Plasma And Its Application To A Pharmacokinetic Study In Turkey
(Oxford Univ Press, 2014)A simple high-performance liquid chromatography method has been developed for the determination of naproxen in human plasma. The method was validated on an Ace C18 column using ultraviolet detection. The mobile phase ... -
Immunomodulation And Oxidative Stress In Denim Sandblasting Workers: Changes Caused By Silica Exposure
(Inst Medical Research & Occupational Health, 2013)Workers in denim sandblasting are at a high risk of developing silicosis, an occupational lung disease caused by inhaling crystalline silica dust. The development and progress of silicosis is associated with the activation ... -
In Vitro Investigation Of The Effects Of Boron Nitride Nanotubes And Curcumin On Dna Damage
(2019)Backround Stem cells provide an opportunity to analyse the effects of xenobiotic on cell viability, differentiation and cell functions. Evaluation of the possible cytotoxic and DNA damaging effects on bone marrow CD34+ ... -
Induction Of Ros, P53, P21 In Dehp- And Mehp-Exposed Lncap Cells-Protection By Selenium Compounds
(Pergamon-Elsevier Science Ltd, 2011)This study was designed to investigate the hypothesis that the toxic effects of di(2-ethylhexyl)phthalate (DEHP), the most abundantly used plasticizer and ubiquitous environmental contaminant that cause alterations in ... -
Intracellular Generation of Ros by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity
(Oxford Univ Press, 2014)Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder ... -
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ... -
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ... -
Modulation Of The Poly (Adp-Ribose) Polymerase Inhibitor Response And Dna Recombination In Breast Cancer Cells By Drugs Affecting Endogenous Wild-Type P53
(Oxford Univ Press, 2014)Synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) and homologous recombination (HR) repair pathways have been exploited for the development of novel mono-and combination cancer therapies. The tumor ... -
Mycotoxin Detection In Maize, Commercial Feed, And Raw Dairy Milk Samples From Assiut City, Egypt
(2019)This survey was conducted to investigate the contamination by multiple mycotoxins, aflatoxins (AFB1, AFB2, AFG1, and AFG2), ochratoxin A (OTA), and zearalenone (ZEA) in 61 samples of maize and 17 commercial animal feed ... -
Neopterin Levels And Indoleamine 2,3-Dioxygenase Activity As Biomarkers Of Immune System Activation And Childhood Allergic Diseases
(2019)Background Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase ... -
Neopterin Profile To Evaluate The Effectiveness Of Treatment In Aggressive Periodontitis
(Walter De Gruyter Gmbh, 2003)Periodontal disease results from the interaction of the host defence mechanisms with the microbial dental plaque. Analysis of gingival crevicular fluid (GCF) provides a non-invasive means of evaluating the role of the host ...