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dc.contributor.authorSaylan, Yeşeren
dc.contributor.authorErdem, Özgecan
dc.contributor.authorÜnal, Serhat
dc.contributor.authorDenizli, Adil
dc.date.accessioned2021-06-09T06:47:10Z
dc.date.available2021-06-09T06:47:10Z
dc.date.issued2019
dc.identifier.issn2079-6374
dc.identifier.urihttp://dx.doi.org/10.3390/bios9020065
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627152/
dc.identifier.urihttp://hdl.handle.net/11655/24864
dc.description.abstractInfectious diseases still pose an omnipresent threat to global and public health, especially in many countries and rural areas of cities. Underlying reasons of such serious maladies can be summarized as the paucity of appropriate analysis methods and subsequent treatment strategies due to the limited access of centralized and equipped health care facilities for diagnosis. Biosensors hold great impact to turn our current analytical methods into diagnostic strategies by restructuring their sensing module for the detection of biomolecules, especially nano-sized objects such as protein biomarkers and viruses. Unquestionably, current sensing platforms require continuous updates to address growing challenges in the diagnosis of viruses as viruses change quickly and spread largely from person-to-person, indicating the urgency of early diagnosis. Some of the challenges can be classified in biological barriers (specificity, low number of targets, and biological matrices) and technological limitations (detection limit, linear dynamic range, stability, and reliability), as well as economical aspects that limit their implementation into resource-scarce settings. In this review, the principle and types of biosensors and their applications in the diagnosis of distinct infectious diseases were comprehensively explained. The deployment of current biosensors into resource-scarce settings is further discussed for virus detection by elaborating the pros and cons of existing methods as a conclusion and future perspective.
dc.language.isoen
dc.relation.isversionof10.3390/bios9020065
dc.rightsAttribution 4.0 United States
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleAn Alternative Medical Diagnosis Method: Biosensors For Virus Detection
dc.title.alternativeAn Alternative Medical Diagnosis Method
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalBiosensors
dc.contributor.departmentKimya
dc.identifier.volume9
dc.identifier.issue2
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus


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Attribution 4.0 United States
Aksi belirtilmediği sürece bu öğenin lisansı: Attribution 4.0 United States