Now showing items 1-4 of 4
Genetic Associations Of The Response To Inhaled Corticosteroids In Asthma: A Systematic Review
There is wide variability in the response to inhaled corticosteroids (ICS) in asthma. While some of this heterogeneity of response is due to adherence and environmental causes, genetic variation also influences response ...
Oxidative Stress And Antioxidant Defense
Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism and environmental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules and can damage ...
The Role Of Scca1 In Asthma Related Physiological Events In The Airway Epithelium And The Effect Of Promoter Variants On Asthma And Gene Function
(W B Saunders Co Ltd, 2013)
Background: Even though the systemic level of SCCA1, a serine protease inhibitor, was shown to be elevated in asthma, its physiological role is unknown. Objective: We sought to determine the effect of SCCA1 on apoptosis, ...
The Effects of an Insertion in the 5 ' Utr of the Amcase on Gene Expression and Pulmonary Functions
(W B Saunders Co Ltd, 2011)
Background: Studies regarding the physiological role of acidic mammalian chitinase (AMCase) and the effects of its genetic variants on asthma have produced conflicting results. Objectives: We aimed to determine the genetic ...