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Toplam kayıt 50, listelenen: 41-50
Endothelial Nitric Oxide Synthase-Dependent Cerebral Blood Flow Augmentation By L-Arginine After Chronic Statin Treatment
(Sage Publications Inc, 2000)
Nitric oxide, a product of nitric oxide synthase activity, relaxes vascular smooth muscle and elevates brain blood flow. We evaluated the importance of eNOS to cerebral blood flow augmentation after L-arginine infusion and ...
Prolonged Therapeutic Window for Ischemic Brain Damage Caused by Delayed Caspase Activation
(Sage Publications Inc, 1998)
Apoptotic cell death is prominent in neurodegenerative disorders, such as Alzheimer's disease and Huntington's disease? and is found in cerebral ischemia. Using a murine model of delayed cell death, we determined that ...
Can Restoring Incomplete Microcirculatory Reperfusion Improve Stroke Outcome After Thrombolysis?
(Sage Publications Inc, 2012)
Substantial experimental data and recent clinical evidence suggesting that tissue reperfusion is a better predictor of outcome after thrombolysis than recanalization necessitate that patency of microcirculation after ...
Systemically Administered Brain-Targeted Nanoparticles Transport Peptides Across the Blood-Brain Barrier and Provide Neuroprotection
(Nature Publishing Group, 2015)
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. ...
Vegf Protects Brain Against Focal Ischemia Without Increasing Blood-Brain Permeability When Administered Intracerebroventricularly
(Sage Publications Inc, 2005)
Delayed administration of vascular endothelial growth factor (VEGF) promotes functional recovery after focal cerebral ischemia. However, early intravenous injection of VEGF increases blood-brain barrier (BBB) leakage, ...
Perioperative Hyperglycemia is a Strong Correlate of Postoperative Infection in Type II Diabetic Patients after Coronary Artery Bypass Grafting
(Japan Endocrine Society, 2002)
This study was planned to assess the relationship of perioperative glycemic control to the subsequent risk of infectious complications and to compare early clinical outcomes of coronary artery bypass surgery in diabetics ...
Natural History Of Congenital Generalized Lipodystrophy: A Nationwide Study From Turkey
(Oxford Univ Press, 2016)
Context: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near-total lack of body fat. Objective: We aimed to study natural history and disease burden of various subtypes ...
Effects Of Testosterone Replacement On Electrocardiographic Parameters In Men: Findings From Two Randomized Trials
(Oxford Univ Press, 2017)
Context: Endogenous testosterone levels have been negatively associated with QTc interval in small case series; the effects of testosterone therapy on electrocardiographic parameters have not been evaluated in randomized ...
Effects Of L-Thyroxine On Gastric Motility And Ghrelin In Subclinical Hypothyroidism: A Prospective Study
(Oxford Univ Press, 2013)
Introduction: Overt hypothyroidism affects the gastrointestinal system. Limited data are available regarding gastric motility in subclinical hypothyroidism (SCH). Objective: The aim of this study was to assess gastric ...
Regulation of Adiponectin Secretion by Adipocytes in the Polycystic Ovary Syndrome: Role of Tumor Necrosis Factor-Alpha
(Oxford Univ Press, 2010)
Context: Adipose tissue dysfunction associated with low-grade chronic inflammation and dysregulation of adipokine secretion might significantly contribute to the pathogenesis of polycystic ovary syndrome (PCOS). Objective: ...