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Toplam kayıt 39, listelenen: 1-10
Exome Sequencing Reveals Cubilin Mutation As A Single-Gene Cause Of Proteinuria
(Amer Soc Nephrology, 2011)
In two siblings of consanguineous parents with intermittent nephrotic-range proteinuria, we identified a homozygous deleterious frameshift mutation in the gene CUBN, which encodes cubulin, using exome capture and massively ...
Mutation Analysis Of Nphs1 In A Worldwide Cohort Of Congenital Nephrotic Syndrome Patients
(Karger, 2012)
Background: Congenital nephrotic syndrome (CNS) is defined as nephrotic syndrome that manifests within the first 3 months of life. Mutations in the NPHS1 gene encoding nephrin, are a major cause for CNS. Currently, more ...
Ureteroneocystostomy In Primary Vesicoureteral Reflux: Critical Retrospective Analysis Of Factors Affecting The Postoperative Urinary Tract Infection Rates
(Brazilian Soc Urol, 2014)
Introduction: To determine the parameters affecting the outcome of ureteroneocystostomy (UNC) procedure for vesicoureteral reflux (VUR). Materials and Methods: Data of 398 patients who underwent UNC procedure from 2001 to ...
Proteasome Inhibitor Bortezomib Increases Radiation Sensitivity in Androgen Independent Human Prostate Cancer Cells
(Elsevier Science Inc, 2010)
OBJECTIVES To investigate the effects of a strong proteasome inhibitor, bortezomib alone or in combination with radiotherapy on androgen-independent DU145 human prostate cancer cells. Proteasomes play important roles in ...
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
(Taylor & Francis Ltd, 2012)
Background: There are few data on the effects of anesthesia and cardiopulmonary bypass (CPB) on perioperative renal function in children with cyanotic congenital heart disease undergoing open heart surgery. This study aims ...
Evaluation Of Apoptosis Indexes In Currently Used Oral Alpha-Blockers In Prostate: A Pilot Study
(Brazilian Soc Urol, 2018)
Objectives: Apoptosis effect of oral alpha-blockers is known in the prostate. Apoptosis index of silodosin has not been proved, yet. Aims are to present apoptosis index of silodosin in prostate and to compare this with ...
Genetic Screening In Adolescents With Steroid-Resistant Nephrotic Syndrome
(Elsevier Science Inc, 2013)
Genetic screening paradigms for congenital and infantile nephrotic syndrome are well established; however, screening in adolescents has received only minor attention. To help rectify this, we analyzed an unselected adolescent ...
Genetic Basis Of Cystinosis In Turkish Patients: A Single-Center Experience
(Springer, 2012)
We report the molecular findings for the CTNS gene in 12 Turkish cystinosis patients aged 7-29 years. All presented initially with severe failure to thrive, polyuria, and polydipsia. Cystinosis was diagnosed at age 1 month ...
Chronic Renal Disease In Children Aged 5-18 Years: A Population-Based Survey In Turkey, The Credit-C Study
(Oxford Univ Press, 2012)
Background. Data on the epidemiology of chronic kidney disease (CKD), which is a serious health problem and refers to a condition related to irreversible kidney damage that further progress to end-stage renal disease in ...
Circulating Supar In Two Cohorts Of Primary Fsgs
(Amer Soc Nephrology, 2012)
Overexpression of soluble urokinase receptor (suPAR) causes pathology in animal models similar to primary FSGS, and one recent study demonstrated elevated levels of serum suPAR in patients with the disease. Here, we analyzed ...