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Toplam kayıt 29, listelenen: 21-29
The Polycystic Ovary Syndrome: A Position Statement From The European Society Of Endocrinology
(Bioscientifica Ltd, 2014)
Polycystic ovary syndrome (PCOS) is the most common ovarian disorder associated with androgen excess in women, which justifies the growing interest of endocrinologists. Great efforts have been made in the last 2 decades ...
Weight-Sparing Effect Of Insulin Detemir: A Consequence Of Central Nervous System-Mediated Reduced Energy Intake?
(Wiley, 2015)
Insulin therapy is often associated with adverse weight gain. This is attributable, at least in part, to changes in energy balance and insulin's anabolic effects. Adverse weight gain increases the risk of poor macrovascular ...
Alpha-Synuclein Aggregation Induced By Brief Ischemia Negatively Impacts Neuronal Survival in Vivo: A Study in [A30P] Alpha-Synuclein Transgenic Mouse
(Sage Publications Inc, 2011)
Alpha-synuclein oligomerization and aggregation are considered to have a role in the pathogenesis of neurodegenerative diseases. However, despite numerous in vitro studies, the impact of aggregates in the intact brain is ...
Can Restoring Incomplete Microcirculatory Reperfusion Improve Stroke Outcome After Thrombolysis?
(Sage Publications Inc, 2012)
Substantial experimental data and recent clinical evidence suggesting that tissue reperfusion is a better predictor of outcome after thrombolysis than recanalization necessitate that patency of microcirculation after ...
Systemically Administered Brain-Targeted Nanoparticles Transport Peptides Across the Blood-Brain Barrier and Provide Neuroprotection
(Nature Publishing Group, 2015)
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. ...
Natural History Of Congenital Generalized Lipodystrophy: A Nationwide Study From Turkey
(Oxford Univ Press, 2016)
Context: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near-total lack of body fat. Objective: We aimed to study natural history and disease burden of various subtypes ...
Effects Of Testosterone Replacement On Electrocardiographic Parameters In Men: Findings From Two Randomized Trials
(Oxford Univ Press, 2017)
Context: Endogenous testosterone levels have been negatively associated with QTc interval in small case series; the effects of testosterone therapy on electrocardiographic parameters have not been evaluated in randomized ...
Effects Of L-Thyroxine On Gastric Motility And Ghrelin In Subclinical Hypothyroidism: A Prospective Study
(Oxford Univ Press, 2013)
Introduction: Overt hypothyroidism affects the gastrointestinal system. Limited data are available regarding gastric motility in subclinical hypothyroidism (SCH). Objective: The aim of this study was to assess gastric ...
Regulation of Adiponectin Secretion by Adipocytes in the Polycystic Ovary Syndrome: Role of Tumor Necrosis Factor-Alpha
(Oxford Univ Press, 2010)
Context: Adipose tissue dysfunction associated with low-grade chronic inflammation and dysregulation of adipokine secretion might significantly contribute to the pathogenesis of polycystic ovary syndrome (PCOS). Objective: ...