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D vitaminin Kognisyon, Fiziksel Fonksiyon ve Ultrasonografik Cilt, Cilt Altı Yağ Dokusu ve Kas Ölçümleri Üzerine Etkilerinin Değerlendirilmesi
(Tıp Fakültesi, 2021)Doğan, Y., Evaluation of the Effects of Vitamin D on Cognition, Physical Function and Ultrasonographic Measurements of Skin, Subcutaneous Fat Tissue and Muscle Measurements, Hacettepe University Medical School, Thesis In ... -
D3-Büyüme Hormon Reseptör Polimorfizminin Akromegalı Hastalarında Klinik, Metabolik ve Kardiyovasküler Etkileri
(Tıp Fakültesi, 2013)Background and aim: A common polymorphic variant of the growth hormone receptor (GHR) consists of genomic deletion of exon 3 (d3-GHR) or full-length genotype (fl-GHR). d3-GHR is associated with increased responsiveness ... -
Dach: Genomic Characterization, Evaluation As A Candidate For Postaxial Polydactyly Type A2, And Developmental Expression Pattern Of The Mouse Homologue
(Academic Press Inc, 2001)The gene DACH is a human homologue of Drosophila melanogaster dachshund (dac), which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. To investigate possible ... -
Dahili ve Cerrahi Bilimler Araştırma Görevlilerinde Tükenmişlik Sendromu Oranlarının Karşılaştırılması ve İşyeri Doyumuyla Olan İlişkisinin Gösterilmesi
(Tıp Fakültesi, 2019)Burnout syndrome; is a psychosocial phenomenon that develops in employees against the intense stress situation in the workplace, especially seen in occupations working in face to face with people. It has been shown in many ... -
Daily Surveillance With Early Warning Scores Help Predict Hospital Mortality In Medical Wards
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: To analyze the potency of a modified early warning score (EWS) to help predict hospital mortality when used for surveillance in nonacute medical wards. Materials and methods: Patients in internal medicine ... -
Dali: Defining Antibiotic Levels In Intensive Care Unit Patients: Are Current Beta-Lactam Antibiotic Doses Sufficient For Critically Ill Patients?
(Oxford Univ Press, 2014)Background. Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether beta-lactam antibiotic dosing in critically ill patients achieves concentrations ... -
Damage assessment in adult IgA vasculitis. Cross-sectional results of a multicentre cohort
(Clinical and Experimental Rheumatology SAS, 2020-02-11)OBJECTIVES: Immunoglobulin (Ig) A vasculitis affects children more commonly than adults and previous literature lacks any formal damage assessment. Our aim in this study is to investigate the disease course, relapse rates ... -
Damak Yarıklarının İn Situ Doku Mühendisliği ile Onarımı: Alveolar Yarık Hayvan Modeli Oluşturulması ve Farklı Rejimlerde Biyobozunur Doku Iskeleleri ile Onarımı
(Tıp Fakültesi, 2014)In this study, the tricalcium phosphate polymer, a tissue scaffold known for its direct effects on tissue healing, and that is used commonly in bone defect models, was upgraded by adding collagen by the Hacettepe University ... -
Data Of Indirect Immunofluorescence Labeling Of The Mouse Brain Sections With Sera From Sle And Ms Patients
(2017)The data presented in this article are related to the research article entitled “Behcet Disease serum is immunoreactive to neurofilament medium which share common epitopes to bacterial HSP-65, a putative trigger” (Lule et ... -
Dctn1 Mutations In Perry Syndrome
(2009)Perry syndrome consists of early-onset parkinsonism, depression, severe weight loss and hypoventilation, in which brain pathology is characterized by TDP-43 immunostaining. Through genome-wide linkage analysis we have ... -
De Novo Mutations In Smchd1 Cause Bosma Arhinia Microphthalmia Syndrome And Abrogate Nasal Development
(Nature Publishing Group, 2017)Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic ... -
Deciphering The Glycosylome Of Dystroglycanopathies Using Haploid Screens For Lassa Virus Entry
(Amer Assoc Advancement Science, 2013)Glycosylated alpha-dystroglycan (alpha-DG) serves as cellular entry receptor for multiple pathogens, and defects in its glycosylation cause hereditary Walker-Warburg syndrome (WWS). At least eight proteins are critical to ... -
Decreased Activity And Genetic Polymorphisms Of Cyp2C19 In Behcet'S Disease
(Wiley, 2017)Behcet's disease (BD) is a systemic autoimmune disorder. Cytochrome P450 enzymes (CYPs) are responsible for various drug metabolism reactions as well as those of endogenous substances which may be associated with autoimmune ... -
Decreased Catalytic Activity And Altered Activation Properties Of Pde6C Mutants Associated With Autosomal Recessive Achromatopsia
(Oxford Univ Press, 2011)Mutations in the gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase (PDE6C) have been recently reported in patients with autosomal recessive inherited achromatopsia (ACHM) and early-onset cone ... -
Decreased Keratocyte Density And Central Corneal Thickness In Primary Open-Angle Glaucoma Patients Undergoing Treatment With Topical Prostaglandin Analogues
(2015)Purpose: To evaluate whether prostaglandin (PG) analogue use is associated with alterations in keratocyte density and central corneal thickness (CCT) in subjects with primary open-angle glaucoma (POAG). Materials and ... -
Decreased Prevalence Of Atopy In Paediatric Patients With Familial Mediterranean Fever
(B M J Publishing Group, 2004)Background: A number of inflammatory diseases, including familial Mediterranean fever (FMF), have been shown to be driven by a strongly dominated Th1 response, whereas the pathogenesis of atopic diseases is associated with ... -
Decreased Serum Paraoxonase 1 (Pon1) Activity: An Additional Risk Factor For Atherosclerotic Heart Disease In Patients With Pcos?
(Oxford Univ Press, 2006)BACKGROUND: Patients with polycystic ovary syndrome (PCOS) may have an increased risk for the development of hypertension and atherosclerotic heart disease (AHD), the pathophysiological mechanisms of which are not clear. ...