Dosya Biçimi"Bilimsel Araştırma Projeleri KB" Tıp Fakültesi için listeleme
Toplam kayıt 164, listelenen: 21-40
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Bilinen Metabolik Hastalıklar ve Sendromlar ile İlişkilendirilemeyen Konjenital/Gelişimsel Kataraktlarda Yeni Nesil Dizileme ile Moleküler Etiyolojinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)The aim of the study was to identify the molecular etiology in patients with congenital/developmental cataract which can not be attributed to known metabolic diseases or syndromes by next generation sequencing. A total of ... -
Bisfenol A’nın Hepg2 Hücrelerine Olan Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Öz, E. Examination of the Effects of Bisphenol A on HepG2 Cells. Hacettepe University Graduate School of Health Sciences, Biochemistry Program, Master Thesis, Ankara, 2020. In this study, it was aimed to determine the ... -
Büyüme Çağındaki Sıçanlarda Oral Kaprilik Asit Uygulamasının Açil Ghrelin ve Büyüme Hormonu Düzeyleri ile Anksiyete Üzerine Etkisi
(Tıp Fakültesi, 2022)Caprylic acid is a medium chain fatty acid containing 8 carbons. Caprylic acid is necessary for the conversion of ghrelin which is known as the hunger hormone, to its active form acyl ghrelin. In addition to its functions ... -
Çocuk Yoğun Bakım Hastalarında Kullanılan Tıbbi Malzemelerin İdrar Bisfenol A Düzeylerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2020-10-01)The exposure of pediatric intensive care patients to Bisphenol A may be different in acute sick children who were healthy beforehand, and chronically sick children, due to the use of multiple and various medical materials. ... -
Çocuklarda Konuşma Gecikmesi ile Plazma Ftalat Düzeyi Arasındaki İlişkinin İncelenmesi
(Tıp Fakültesi, 2020)Speech delay is one of the most common developmental problems seen in preschool children. Therefore, being able to diagnose and identify underlying causes and risk factors is very important for timely intervention and ... -
Çocukluk Çağı Otozomal Dominant ve Otozomal Resesif Polikistik Böbrek Hastalıklarının Klinik ve Genetik Özelliklerinin Araştırılması
(Tıp Fakültesi, 2021-02-19)Tutal, O, Clinical and Mutational Spectrum of Children with Autosomal Recessive and Autosomal Dominant Polycystic Kidney Disease, Hacettepe University Faculty of Medicine, Department of Pediatrics, Thesis of Pediatrics, ... -
Deneysel Parkinson Hastalığı Modelinde Obezitenin Motor Becerilere Etkisi ve Beyin Tirozin Hidroksilaz Düzeyi, Dopaminerjik Reseptörler ve Leptin Reseptörleri ile İlişkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03)Excessive increase in body weight, which has already become a public health problem, is also associated with many diseases. On the other hand, prolonged life expectancy also increases the incidence of neurodegenerative ... -
Deneysel Sıçan Hidrosefali Modelinde Deksmedetomidinin Nöroenflamasyonun Üzerine Etkilerinin Radyolojik Olarak İncelenmesi
(Tıp Fakültesi, 2022-10-27)ABSTRACT Yahya D. Radiological investigation of the effects of dexmedetomidine on hydrocephalus induced neuroinflamation in experimental rat hydrocephalus model, Hacettepe University Faculty of Medicine, Department ... -
DENEYSEL YANIK MODELİNDE, STAZ ZONUNDA TOPİKAL AJANLARIN YARA İYİLEŞMESİNE ETKİLERİ
(Tıp Fakültesi, 2023-12-12)As a result of thermal damage to the skin, a burn wound consists of hyperemia on the outer layer, stasis in the middle zone and coagulation zones in the innermost region. Despite the absence of ischemic signs in the stasis ... -
Desma Mutant Zebra Balığı Modelinde Tedavi Amaçlı Xmu-Mp-1 Uygulaması
(Sağlık Bilimleri Enstitüsü, 2021)In this thesis, the application of XMU-MP-1 drug candidate molecule which is a MST1 / 2 kinase inhibitor and selectively inhibits the Hippo pathway was performed by mixing the drug with zebrafish embryo egg water or adult ... -
Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease
(Sağlık Bilimleri Enstitüsü, 2020-07-07)Sickle cell disease (SCD) is a hemoglobinopathy that causes severe anemia and is characterized by lipid abnormalities, oxidative stress and chronic inflammation. It is caused by a single point-mutation in the beta globin ... -
Diyabet Hastalarında Mineral Trioksit Agregat/1α,25-Dihidroksivitamin D3 Kombinasyonu İle Dental Pulpa Kök Hücrelerinde Odontojenik Farklılaşmanın Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-01-15)Dental treatments in diabetic patients have been reported to fail in the long term and these patients have more tooth extraction. It is aimed to investigate the odonto/osteogenic differentiation potential of the combination ... -
Diyabetik Ayak Gelişen Hastalarda Angiopoietin Benzeri Protein-4 ve Follistatin Benzeri 1 Protein Düzeyleri ile Angiopoietin Benzeri Protein-4 Gen Polimorfizmi
(Tıp Fakültesi, 2019)Angiopoietin-like protein-4 (ANGPTL-4) is an angiopoietin-like protein that plays an important role in wound healing, lipid, and glucose metabolism. Follistatin-like 1 (FSTL1) is a cardiokin with effects on angiogenesis ... -
DİYABETİK KETOASİDOZLU HASTALARDA MİYOKİN PROFİLİNİN DEĞERLENDİRİLMESİ
(Tıp Fakültesi, 2023)The effects of myokines mainly released from the muscle tissue on glucose and lipid metabolism are still under investigation, and their roles in the pathogenesis of diabetic ketoacidosis (DKA) are yet unknown. In this ... -
DOCK8 Eksikliği Olan Hastalarda T Hücre Reseptör Repertuvarının Yeni Nesil Dizileme İle Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Identification of immüne repertoire is crucial to characterize adaptive immüne responses in terms of disease approach. V(D)J recombination is one of the most crucial factors in the development of the immune repertoire. ... -
Doksorubisin Uygulanan Üçlü Negatif Meme Kanserinde Taurinin Tümör Büyüklüğü ve Metastaz Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Gedikli, E., The Effect of Taurine on Tumor Size and Metastasis in Triple Negative Breast Cancer Treated With Doxorubicin, Hacettepe University Graduate School of Health Sciences Physiology Program PhD Thesis, Ankara, 2023. ... -
Dışkı ve Mide Biyopsi Örneklerinden Helıcobacter Pylorı Enfeksiyonunun ve Klaritromisin Direncinin Moleküler Yöntemler ile Saptanması
(Tıp Fakültesi, 2022)Inal Neşe, Detection of Helicobacter pylori Infection and Clarithromycin Resistance in Stool and Gastric Biopsy Samples by Molecular Methods, Hacettepe University Faculty of Medicine, Department of Medical Microbiology, ... -
Endometrial Stromal Hücrelerde Ovaryan Hormonlar ile CKAP4 İlişkisinin İncelenmesi
(Tıp Fakültesi, 2023)Endometrial stromal cells undergo changes in the menstrual cycle and decidualization with the effect of ovarian hormones. Disruptions in these processes may result in clinical outcomes such as infertility, recurrent pregnancy ... -
Epilepsi Hastalarında, Serum ve Beyin Omurilik Sıvısındaki Oreksin Seviyesinin Uyku Evreleri ve Nöbetlerle İlişkisi
(Tıp Fakültesi, 2020)One of the unknown mechanisms in epilepsy pathogenesis is protein called orexin. Although the relation of orexin to sleep has been revealed, its place in epilepsy has not been fully clarified yet. In this study, we aimed ... -
Erişkin tipi difüz gliomların tiplendirilmesinde moleküler yöntemlere alternatif olarak immünhistokimyasal vekil biyobelirteçlerin kullanımı
(Tıp Fakültesi, 2023)Adult-type IDH (isocitrate dehydrogenase)-mutant diffuse gliomas are divided into two groups as astrocytoma, IDH-mutant and oligodendroglioma, IDH-mutant and 1p/19q codeleted, on the basis of 1p/19q status. According ...