• Hdac4 Mutations Cause Diabetes And Induce Β‐Cell Foxo1 Nuclear Exclusion 

      Gong, Maolian; Yu, Yong; Liang, Lei; Vuralli, Dogus; Froehler, Sebastian; Kuehnen, Peter; Du Bois, Philipp; Zhang, Jingjing; Cao, Aidi; Liu, Yuantao; Hussain, Khalid; Fielitz, Jens; Jia, Shiqi; Chen, Wei; Raile, Klemens (2019)
      Background Studying patients with rare Mendelian diabetes has uncovered molecular mechanisms regulating β‐cell pathophysiology. Previous studies have shown that Class IIa histone deacetylases (HDAC4, 5, 7, and 9) modulate ...