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dc.contributor.authorYilmaz, Melek Tugce
dc.contributor.authorElmali, Aysenur
dc.contributor.authorYazici, Gozde
dc.date.accessioned2019-12-10T11:30:40Z
dc.date.available2019-12-10T11:30:40Z
dc.identifier.issn2168-8184
dc.identifier.urihttps://doi.org/10.7759/cureus.3860
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414182/
dc.identifier.urihttp://hdl.handle.net/11655/15796
dc.description.abstractThe abscopal effect is mediated by a systemic anti-tumor immune response and reflects the regression of non-irradiated metastatic lesions at a distance from the primary site of irradiation. This review will focus on understanding the biological rationale behind the abscopal effect of radiotherapy (RT), which has a recently renewed interest as a result of the successes achieved with immunotherapy and RT in combination. Both RT and immunotherapy are standard components of modern treatment regimens. Combination of these two modalities results in an increased response in the irradiated lesions themselves and the metastatic regions distant from the site of irradiation. We will summarize the abscopal effect of radiotherapy, in particular, the synergistic effect of RT and immunotherapy.
dc.relation.isversionof10.7759/cureus.3860
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleAbscopal Effect, From Myth To Reality: From Radiation Oncologists' Perspective
dc.typeinfo:eu-repo/semantics/article
dc.relation.journalCureus
dc.contributor.departmentRadyasyon Onkolojisi
dc.identifier.volume11
dc.identifier.issue1
dc.description.indexPubMed


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