Erişkinlerde Keçiboynuzu Ununun Kan Lipit Profiline Etkisi

Abstract

The aim of the survey is to find the effect of consuming carob flour on the blood lipid profile in adults. A total of 20 adults (35-60 years old, 10 male and 10 female), with high triglycerides (360 mg/dL), and/or total cholesterol (200 mg/dL), and body mass index (BMI) above 25 kg/m2 with no diet-related chronic diseases, not consuming alcoholic drinks, not smoking and using medicines regularly, not taking food supplements during the last year were included in the study. Subjects consumed carob flour for 2 months, for 10 g/day. At the beginning of the study, dietary intake recalls were determined for 2 consecutive days (one day of a week and a weekend) and biochemical measures were assessed for three times (at the beginning, first month and second month). Out of total, 80.0% of females and 70.0% of males were classified as overweight according to BMI and 40.0% of males and 80.0% of females were found physically inactive (p>0.05). Total fat, monounsaturated fatty acids (MUFA) and total cholesterol intakes of males were higher than females during the weekends (p<0.05). Dietary fiber intakes were higher during the week, both in males and females (p>0.05). Daily carob flour consumption reduced total cholesterol level by 7.89±13.03% in the first month and 13.72±13.36% in the second month (p<0.01). Also statistically significant decrease was determined in total serum lipids by 14.89±16.09% (p<0.01). Significant decrease in serum triglycerides level was determined in males but not in females (p>0.05). Low density lipoprotein (LDL) cholesterol levels were decreased (Both gender: 1st month: 8.90±23.25% and 2nd month 13.09±14.77%; males: 13.27±17.34%; females: 12.90±12.63%) (p<0.05). No significant differences were found in high density lipoprotein (HDL) cholesterol, LDL/HDL cholesterol ratio, Apo A-1 levels increased only in females (p<0.05). No significant changes were determined in Apo B-100 and total serum bilirubin levels (p>0.05). Carob flour caused reduction in blood lipids and could be used for the control.