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Smooth Muscle Cells Isolated from Thoracic Aortic Aneurysms Exhibit Increased Genomic Damage, but Similar Tendency for Apoptosis
(Mary Ann Liebert, Inc, 2012)
Aortic aneurysms (AA) are characterized by structural deterioration leading to progressive dilation. During the development of AA, two key structural changes are pronounced, one being degradation of extracellular matrix ...
The Effect of Acute Myeloid Leukemia Cells Expressing PD-L2 Co-Stimulatory Molecule on Helper T Cell Activation
(Sağlık Bilimleri Enstitüsü, 2017-07-25)
The binding of PD-1 to its ligands (PD-L1 and PD-L2) inhibits and/or regulates T cell responses. Myeloid leukemia cells can express both co-activatory and co-inhibitory molecules simultaneously. The function of PD-L1 in ...
Vajinal Kaf Brakiterapi Uygulamaları için Yoğunluk Ayarlı Aplikatör Tasarımı: Dozimetrik Fizibilite Çalışması
(Kanser Enstitüsü, 2018)
Depending on technological advances in radiotherapy, the use of three-dimensional (3D) treatment planning in brachytherapy (BRT) applications has provided a great advantage in terms of efficacy of treatment in gynecological ...
Lung Cancer Screening: A Comprehensive Review of the Literature with Detailed Data
(Akad Doktorlar Yayınevi, 2014)
Lung cancer still has a big proportion of cancer related deaths inspite of improvements in chemotherapeutic and surgical treatment approaches. It has a strong relationship with tobacco comsumption so that it can be regard ...
Cytoreductive Surgery For Intestinal Cancer Patients Metastatic To Ovaries Presenting As Primary Ovarian Cancer
(Akad Doktorlar Yayınevi, 2016)
Colorectal cancer accounts for one third of non-genital tumors metastasize to the ovaries. We aimed to investigate the role of cytoreductive surgery in colon and small intestinal cancer patients with adnexal metastases, ...
Mean Esophageal Radiation Dose is Predictive of the Grade of Acute Esophagitis in Lung Cancer Patients Treated with Concurrent Radiotherapy and Chemotherapy
(Oxford Univ Press, 2012)
The intention of this research was to define the predictive factors for acute esophagitis (AE) in lung cancer patients treated with concurrent chemotherapy and three-dimensional conformal radiotherapy. The data for 72 lung ...
Cancer Trends and Incidence and Mortality Patterns in Turkey
(Oxford Univ Press, 2011)
Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ...
Effect of Zoledronic Acid on Rats' Tissue Sdf-1 Expression
(Akad Doktorlar Yayınevi, 2016)
Zoledronic acid has been shown to inhibit cancer cell proliferation, metastasis and induce cancer cell apoptosis. Stromal Derived Factor-1 (SDF-1) is a chemokine that has been reported to be expressed markedly high in the ...
Meme Kanserinde, Normal Fibroblastlar ve Kanserle İlişkili Fibroblastların Monosit Çağrılması, Makrofaj Polarizasyonu ve İnvazyona Etkisi
(Kanser Enstitüsü, 2018)
GÖK YAVUZ B., The Effect of Cancer Associated Fibroblasts and Normal Fibroblasts on Monocyte Recruitment, Macrophage Polarization and Invasion in Breast Cancer. Hacettepe University Institute of Health Sciences Ph.D Thesis ...