Temel Tıp Bilimleri Bölümü Bildiri / Sunu / Poster Koleksiyonuhttps://hdl.handle.net/11655/5092024-03-29T12:10:46Z2024-03-29T12:10:46ZThe Role Of Reactive Oxygen Species And Oxidative Stress In Carbon Monoxide Toxicity: An In-Depth AnalysisAkyol, SümeyyaErdoğan, Serpilİdiz, NuriÇelik, SafaKaya, MehmetUçar, FatmaDane, ŞenolAkyol, Ömerhttps://hdl.handle.net/11655/222712020-09-18T08:32:00Z2014-01-01T00:00:00ZThe Role Of Reactive Oxygen Species And Oxidative Stress In Carbon Monoxide Toxicity: An In-Depth Analysis
Akyol, Sümeyya; Erdoğan, Serpil; İdiz, Nuri; Çelik, Safa; Kaya, Mehmet; Uçar, Fatma; Dane, Şenol; Akyol, Ömer
The underlying mechanism of the central nervous system (CNS) injury after acute carbon monoxide (CO) poisoning is interlaced with multiple factors including apoptosis, abnormal inflammatory responses, hypoxia, and ischemia/reperfusion-like problems. One of the current hypotheses with regard to the molecular mechanism of CO poisoning is the oxidative injury induced by reactive oxygen species, free radicals, and neuronal nitric oxide. Up to now, the relevant mechanism of this injury remains poorly understood. The weakening of antioxidant systems and the increase of lipid peroxidation in the CNS have been implicated, however. Accordingly, in this review, we will highlight the relationship between oxidative stress and CO poisoning from the perspective of forensic toxicology and molecular toxicology.
2014-01-01T00:00:00ZThe Impact Of Standardized Patients' Feedback On The Students' Motivational LevelsTuran, S.Uner, S.Elcin, M.https://hdl.handle.net/11655/163782020-06-15T13:14:15Z2009-01-01T00:00:00ZThe Impact Of Standardized Patients' Feedback On The Students' Motivational Levels
Turan, S.; Uner, S.; Elcin, M.
In this study, we focused on the impact of standardized patients' feedback on the motivational levels of learners for learning communication skills. A control group post-test design was used. The students had two standardized patient encounters in addition to training and debriefing sessions. The students in the study group received face-to-face feedback after the first encounters; but not the control group. We used the motivation dimension of Motivated Strategies for Learning Questionnaire. The standardized patients' feedback effected students' motivational levels. The students who received feedback had lower levels of test anxiety, and higher levels of self-efficacy. (C) 2009 Elsevier Ltd. All rights reserved.
2009-01-01T00:00:00ZMixture Of Learners For Cancer Stem Cell Detection Using Cd13 And H&E Stained ImagesOguz, OguzhanAkbas, Cem EmreMallah, MaenTasdemir, KasimGuzelcan, Ece AkhanMuenzenmayer, ChristianWittenberg, ThomasUner, AysegulCetin, A. EnisAtalay, Rengul Cetinhttps://hdl.handle.net/11655/162762020-02-17T13:58:33Z2016-01-01T00:00:00ZMixture Of Learners For Cancer Stem Cell Detection Using Cd13 And H&E Stained Images
Oguz, Oguzhan; Akbas, Cem Emre; Mallah, Maen; Tasdemir, Kasim; Guzelcan, Ece Akhan; Muenzenmayer, Christian; Wittenberg, Thomas; Uner, Aysegul; Cetin, A. Enis; Atalay, Rengul Cetin
In this article, algorithms for cancer stem cell (CSC) detection in liver cancer tissue images are developed. Conventionally, a pathologist examines of cancer cell morphologies under microscope. Computer aided diagnosis systems (CAD) aims to help pathologists in this tedious and repetitive work. The first algorithm locates CSCs in CD13 stained liver tissue images. The method has also an online learning algorithm to improve the accuracy of detection. The second family of algorithms classify the cancer tissues stained with H&E which is clinically routine and cost effective than immunohistochemistry (IHC) procedure. The algorithms utilize 1D-SIFT and eigen-analysis based feature sets as descriptors. Normal and cancerous tissues can be classified with 92.1% accuracy in H&E stained images. Classification accuracy of low and high-grade cancerous tissue images is 70.4%. Therefore, this study paves the way for diagnosing the cancerous tissue and grading the level of it using HSLE stained microscopic tissue images.
2016-01-01T00:00:00ZIn What Level And How Medical Students Use Metacognition? A Case From Hacettepe UniversityTuran, SevgiDemirel, Ozcanhttps://hdl.handle.net/11655/162322020-04-30T10:33:46Z2010-01-01T00:00:00ZIn What Level And How Medical Students Use Metacognition? A Case From Hacettepe University
Turan, Sevgi; Demirel, Ozcan
The aim of this study is to describe in what level and how medical students use metacognition. In the study, quantitative and qualitative methods were used together, by benefiting from descriptive method. The first three year (preclinic year) students of Hacettepe University, Faculty of Medicine participated to the study. In order to determine the metacognition level, Metacognition Scale was used and also 9 students were interviewed. In the metacognition scores, the differences were determined according to the phases and academic achievement levels but not gender and the curricular language. In the interviews, it's been observed that the students in the learning process go through similar cognitive stages. These stages are recalling knowledge, learning new information and ensuring the sustainability of learning.
2010-01-01T00:00:00Z