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Toplam kayıt 20, listelenen: 1-20
Effect of Insulin on The Mrna Expression of Procollagen N-Proteinases in Chondrosarcoma Oums-27 Cells
(Spandidos Publ Ltd, 2015)
Chondrosarcoma is one of the most common bone tumors, and at present, there is no non-invasive treatment option for this cancer. The chondrosarcoma OUMS-27 cell line produces proteoglycan and type II, IX, and XI collagens, ...
Synergistic Effects of Cisplatin and Proteasome Inhibitor Bortezomib on Human Bladder Cancer Cells
(Spandidos Publ Ltd, 2015)
The proteasome inhibitor bortezomib is a promising novel agent in bladder cancer therapy; however, inducible cytoprotective mechanisms may limit its potential efficacy. To date, the cellular and molecular effects of ...
Prognostic Factors in Malignant Pleural Mesothelioma: A Retrospective Study of 60 Turkish Patients
(Wolters Kluwer Medknow Publications, 2015)
Aim: Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis. The study aims to examine the effect of certain clinical, laboratory, radiologic, and pathologic characteristics on survival. Patients ...
The Efficacy of Delayed Surgery in Children with High-Risk Neuroblastoma
(Wolters Kluwer Medknow Publications, 2015)
Context: Surgery is an important part of treatment in children with neuroblastoma; however, exact timing is unclear. Both initial and delayed surgery was suggested as the best by numerous studies. Aims: Thus, we aimed to ...
Induction Of Telomere Dysfunction Mediated By The Telomerase Substrate Precursor 6-Thio-2'-Deoxyguanosine
(Amer Assoc Cancer Research, 2015)
The relationships between telomerase and telomeres represent attractive targets for new anticancer agents. Here, we report that the nucleoside analogue 6-thio-2'-deoxyguanosine (6-thio-dG) is recognized by telomerase and ...
Assessing The Carcinogenic Potential Of Low-Dose Exposures To Chemical Mixtures In The Environment: The Challenge Ahead
(Oxford Univ Press, 2015)
Low-dose exposures to common environmental chemicals that are deemed safe individually may be combining to instigate carcinogenesis, thereby contributing to the incidence of cancer. This risk may be overlooked by current ...
Clinical Outcomes Of Patients With Advanced Gastrointestinal Stromal Tumors: Safety And Efficacy In A Worldwide Treatment-Use Trial Of Sunitinib
(Wiley-Blackwell, 2015)
BACKGROUNDThe objectives of this study were to provide sunitinib to patients with gastrointestinal stromal tumor (GIST) who were otherwise unable to obtain it and to collect broad safety and efficacy data from a large ...
Do Yoga and Aerobic Exercise Training Have Impact on Functional Capacity, Fatigue, Peripheral Muscle Strength, And Quality of Life In Breast Cancer Survivors?
(Sage Publications Inc, 2015)
Aim. The aim of the study was to compare the effects of aerobic exercise training and yoga on the functional capacity, peripheral muscle strength, quality of life (QOL), and fatigue in breast cancer survivors. Material and ...
Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)
Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ...
Evaluation Of The Effect Of Changes In Dose Rate On Rat Lung Cells
(Sage Publications Inc, 2015)
The aim of this study is to evaluate the effect of dose rate (DR) on lung tissue. The rats included in the study were randomly grouped into 3 groups: Group (G) 1 was defined as control group, and in this group rats were ...
Interleukin-1 Induced Nuclear Factor-B Binds to a Disintegrin-Like and Metalloproteinase with Thrombospondin Type 1 Motif 9 Promoter in Human Chondrosarcoma Cells
(Spandidos Publ Ltd, 2015)
Nuclear factor-B (NF-B) is involved in the regulation of inflammation-associated genes. NF-B forms dimers which bind with sequences referred to as NF-B sites (9-11 bp). A disintegrin-like and metalloproteinase with ...
Future Opportunities in Preventing Ototoxicity: Caffeic Acid Phenethyl Ester May Be A Candidate
(Spandidos Publ Ltd, 2015)
Caffeic acid phenethyl ester (CAPE) is an important active component of propolis, which is derived from honeybee hives. It has received increasing attention in a variety of medical and pharmaceutical research, due to its ...
Kemoterapi Alan Kanserli Çocuklarda Oral Mukozit Gelişimi ve Beslenme Durumu Ilişkisi
(Sağlık Bilimleri Enstitüsü, 2015)
This study was planned and conducted to evaluate
the effect of chemotherapy on development of mucositis and its association with
nutritional status in hospitalized children treated with chemotherapy. Sixty patients,
who ...
Problematic Areas Related to Sexual Life of Individuals with Gynecological Cancer: A Qualitative Study in Turkey
(Akad Doktorlar Yayınevi, 2015)
This study was conducted to examine problematic areas related to sexual life of individuals with gynecological cancer. Qualitative phenomenological research design was used in the study. The data were collected through ...
Does Metabolic Syndrome or Its Components Associate With Prostate Cancer When Diagnosed on Biopsy?
(Sage Publications Inc, 2015)
Purpose: To investigate the association between metabolic syndrome and prostate cancer risk in Turkish men. Methods: We examined data from 220 patients with prostate cancer and 234 men in a control group with benign biopsy ...
Changes Of The Expressions Of Orphan And Gon-Adamts In Chondrosarcoma Cells
(Akad Doktorlar Yayınevi, 2015)
Some of A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) enzymes have been suggested to facilitate invasion and metastasis in cancer. ADAMTS20 is called gon-ADAMTS and ADAMTS10 and -17 are called ...
Long-Term Outcome of Patients with Spinal Myxopapillary Ependymoma: Treatment Results from the Md Anderson Cancer Center and Institutions from the Rare Cancer Network
(Oxford Univ Press, 2015)
Background. Spinal myxopapillary ependymomas (MPEs) are slowly growing ependymal gliomas with preferential manifestation in young adults. The aim of this study was to assess the outcome of patients with MPE treated with ...
Generic Imatinib Mesylate Is As Effective As Original Glivec In The Clinical Management Of Cml
(Akad Doktorlar Yayınevi, 2015)
Unsustainable drug prices in chronic myeloid leukemia (CML) and cancer may be causing harm to patients. The aim of this multi-center study is to assess the efficacy of generic imatinib mesylate (IM) over Glivec in terms ...
Review of Current Status of Radiotherapy Facilities And Assessment of Required Time For Radiotherapy Delivery Workflow in Turkey: On Behalf of Turkish Society For Radiation Oncology
(Akad Doktorlar Yayınevi, 2015)
The aim this study is to evaluate current status and workload of radiotherapy (RT) centers in Turkey, by assessing time and staff required during core treatment procedures in patients with different tumor sites. A survey ...
Safety and Efficacy of Ankaferd Hemostat (Abs) in the Chemotherapy-Induced Oral Mucositis
(Akad Doktorlar Yayınevi, 2015)
Oral mucositis, characterized by ulcerative lesions in the oral mucosa of patients undergoing chemotherapy, is currently considered to be the most severe complication of anti-cancer therapy which is affecting 40-80% of ...