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Toplam kayıt 6, listelenen: 1-6
The Inflammatory Cytokine Tumor Necrosis Factor-Alpha Generates An Autocrine Tumor-Promoting Network In Epithelial Ovarian Cancer Cells
(Amer Assoc Cancer Research, 2007)
Constitutive expression of the inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) is characteristic of malignant ovarian surface epithelium. We investigated the hypothesis that this autocrine action of TNF-alpha ...
Antiadhesive Effects of Grn163L - An Oligonucleotide N3 '-> P5 ' Thio-Phosphoramidate Targeting Telomerase
(Amer Assoc Cancer Research, 2007)
We determined previously that a novel human telomerase RNA (hTR) antagonist, GRN163L, inhibited the tumorigenic potential of A549-luciferase (A549-luc) lung cancer cells in vitro and in vivo. Further studies revealed that ...
Rational Drug Redesign to Overcome Drug Resistance in Cancer Therapy: Imatinib Moving Target
(Amer Assoc Cancer Research, 2007)
Protein kinases are central targets for drug-based cancer treatment. To avoid functional impairment, the cell develops mechanisms of drug resistance, primarily based on adaptive mutations. Redesigning a drug to target a ...
Diarrhea In Neutropenic Patients: A Prospective Cohort Study With Emphasis On Neutropenic Enterocolitis
(Oxford Univ Press, 2007)
Background: Although diarrhea is a frequent complication in neutropenic patients, its true incidence, risk factors and clinical course have not been investigated prospectively. Patients and methods: The study was carried ...
Wwox And Ap2 Gamma Expression Levels Predict Tamoxifen Response
(Amer Assoc Cancer Research, 2007)
Purpose: Assessment of expression levels of Wwox, Wwox- interacting proteins Ap2 alpha, Ap2 gamma, and ErbB4, the Ap2 gamma transcriptional target protein Her2, and the possible Ap2 alpha transcriptional target Prka Rl ...
A Cadaveric Histological Investigation of the Prostate with Three-Dimensional Reconstruction for Better Results in Continence and Erectile Function After Radical Prostatectomy
(Nature Publishing Group, 2007)
In this study our aim is to increase the understanding of the prostate and related organs anatomy for better continence and erectile function results after urological surgery. Prostate and related organs were dissected ...