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In Vitro Activities Of Antibiotics Alone And In Combination Against Brucella Melitensis At Neutral And Acidic Phs
(Amer Soc Microbiology, 1999)
Brucellae survive acidic pHs in phagolysosomes. Azithromycin, streptomycin, and quinolones were active against Brucella melitensis at pH 7.0 but not at pH 5.0; rifampin and doxycycline retained activity at pH 5.0. Regardless ...