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Toplam kayıt 17, listelenen: 1-17
Aryl Butenoic Acid Derivatives As A New Class Of Histone Deacetylase Inhibitors: Synthesis, In Vitro Evaluation, And Molecular Docking Studies
(Scientific Technical Research Council Turkey-Tubitak, 2014)
New aryl butenoic acid derivatives have been synthesized by combining hydroxy- or methoxy-substituted phenyl rings as the capping group, with a double bond in the short linker as well as metal binding groups, enoic ester, ...
Microwave-Assisted Synthesis Of Condensed 1,4-Dihydropyridines As Potential Calcium Channel Modulators
(Scientific Technical Research Council Turkey-Tubitak, 2015)
This study reports the design, synthesis, and calcium channel modulatory activity evaluation of a series of 14 novel fused 1,4-dihydropyridine derivatives. The molecular design of the compounds was based on modifications ...
Synthesis and Molecular Modeling Studies of Naproxen-Based Acyl Hydrazone Derivatives
(Scientific Technical Research Council Turkey-Tubitak, 2015)
A series of N-acylhydrazone derivatives (2a-2p) containing 6-methoxy-naphthalene and acylhydrazone moieties were synthesized in good yield using microwave irradiation and developed as potential COX-2 inhibitors. Furthermore, ...
Experimental And Theoretical Investigation Of The Reaction Between Co2 And Carbon Dioxide Binding Organic Liquids
(Scientific Technical Research Council Turkey-Tubitak, 2016)
The reaction kinetics of CO2 absorption into new carbon dioxide binding organic liquids (CO(2)BOLs) was comprehensively studied to evaluate their potential for CO2 removal. A stopped-flow apparatus with conductivity detection ...
Evaluation Of A Capillary Electrophoresis Method For Routine Determination Of Varenicline Tartrate In Quality-Control Laboratories
(Soc Chemists Technologists Madeconia, 2015)
In this study, analyses were carried out on a fused-silica capillary (i.d. 50.0 mu m, total length 48.5 cm, and effective length 40.0 cm) in normal mode by applying a voltage of 20 kV. Sample injections were made in ...
Optimization Of A Gas Chromatography-Mass Spectrometry Method Using Chemometric Techniques For The Determination Of Ezetimibe In Human Plasma
(Scientific Technical Research Council Turkey-Tubitak, 2013)
A new, rapid, and sensitive gas chromatography-mass spectrometry (GC-MS) method was developed for the determination of ezetimibe (EZE) in human plasma. EZE was derivatized prior to GC-MS analysis. Various derivatization ...
Preparation and Physicochemical Characterizations of Solid Lipid Nanoparticles Containing Dotap for Dna Delivery
(Scientific Technical Research Council Turkey-Tubitak, 2015)
The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ...
Synthesis of Novel 5-Substituted Phenyl-3-(P-Isopropylpheny1)-1-Phenylformazan and Their Biological Activities
(Scientific Technical Research Council Turkey-Tubitak, 2017)
Novel 1-substituted 3-(p-isopropylphenyl)-5-phenylformazans (3a-g) were synthesized and characterized by elemental analysis, H-1 NMR, and FT-IR techniques and UV-visible spectroscopy. Antiproliferative activities of 3a-g ...
Poly-(L)-Histidine Immobilized Cryogels for Lysozyme Purification
(Sage Publications Inc, 2016)
Immobilized metal ion affinity chromatography is one of the methods used for the adsorption of proteins. In this study, poly(glycidyl methacrylate) cryogel discs were prepared by free radical polymerization. The metal ...
An Ionic Liquid/Bismuth Film-Modified Sensor For The Electrochemical Detection of Cefixime
(Scientific Technical Research Council Turkey-Tubitak, 2018)
A highly sensitive and simple method based on an ionic liquid/ex situ bismuth film-modified single-use pencil graphite electrode (IL/Bi/PGE) was offered for the electrochemical detection of cefixime (CEF) for the first ...
A Combined First Principles TDDFT and Experimental Study on the Uv-Vis Spectra Properties of M(P-Nitrophenyl Azo Resorcinol)(3) Complexes (M: Fe, Cr)
(Scientific Technical Research Council Turkey-Tubitak, 2014)
UV-Vis absorption data of p-nitrophenyl azo resorcinol (Magneson I) and its 2 Fe(III) and Cr(III) complexes were investigated both experimentally and theoretically. The geometries were optimized at BP86/TZVP level. The ...
Comparative Study Of Microwave-Assisted And Conventional Synthesis Of Ibuprofen-Based Acyl Hydrazone Derivatives
(Scientific Technical Research Council Turkey-Tubitak, 2013)
A series of potential biological active acyl hydrazone derivatives containing ibuprofen moiety (compounds 4a-4p) was synthesized by the condensation of ibuprofen hydrazone with aromatic aldehydes using conventional and ...
Immobilization Of Laccase Onto A Porous Nanocomposite: Application For Textile Dye Degradation
(Scientific Technical Research Council Turkey-Tubitak, 2016)
Poly(MA-alt-MVE)-g-PLA/ODA-MMT nanocomposite was prepared by self-catalytic interlamellar graft copolymerization of L-lactic acid (LA) onto poly(maleic anhydride-alt-methyl vinyl ether) copolymer in the presence of octadecyl ...
Immobilized Metal Ion Affinity Nanospheres For Alpha-Amylase Immobilization
(Scientific Technical Research Council Turkey-Tubitak, 2014)
Immobilized metal chelate affinity chromatography (IMAC) support was practiced for alpha-amylase immobilization. Poly(hydroxyethylmethacrylate-methacryloylamidotryptophan)-Ni2+ [p(HEMA-MAT)-Ni2+] nanospheres, average ...
Facile Synthesis Of Heteroaryl Substituted Gamma-Lactams From Nitrovinyl Arenes
(Scientific Technical Research Council Turkey-Tubitak, 2018)
Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were ...
An Efficient Water-Mediated Synthetic Route For The Alkylation of Heteroarenes
(Scientific Technical Research Council Turkey-Tubitak, 2018)
An efficient synthetic route has been described for the alkylation of 1H-indole, 1H-benzimidazole, and 1H-benzotriazole. This approach features the alkylation of heteroaromatics through in situ generated enones from ketonic ...
Effect of Sonic Treatment on The Permeation Performance of Cellulose Acetate Membranes Modified By N-Sio2
(Scientific Technical Research Council Turkey-Tubitak, 2015)
Cellulose acetate (CA) membranes were modified by nano-silicon dioxide (n-SiO2), and they were exposed to ultrasonic waves at a frequency of 35 kHz. The effect of sonication on their water sorption tendency and permeation ...