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Toplam kayıt 25, listelenen: 1-20
Mefv Mutations In Systemic Jia
(BioMed Central, 2008)
Background: Systemic form of juvenile idiopathic arthritis (JIA) is regarded as an autoinflammatory disease. Certain genetic polymorphisms in genes coding inflammatory proteins have been associated with the disease. On the ...
Mutation Analysis Of The Pink1 Gene In 391 Patients With Parkinson Disease
(Amer Medical Assoc, 2008)
Objectives: To determine the frequency, distribution, and clinical features of Parkinson disease (PD) with PINK1 mutations. Design: Retrospective clinical and genetic review. Setting: University hospital. Patients: We ...
Mutations in A Human Robo Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis
(Amer Assoc Advancement Science, 2004)
The mechanisms controlling axon guidance are of fundamental importance in understanding brain development. Growing corticospinal and somatosensory axons cross the midline in the medulla to reach their targets and thus form ...
Performance of Three Pcr Methods Targeting Different Regions of Viral Genome for the Detection of Ttv in Non A-E Hepatitis, Chronic B and C Hepatitis and Healthy Blood Donors
(Springer, 2006)
TT virus (TTV) was suggested to be the etiologic agent for non A-E hepatitis but this could not yet be proven due to high detection rates not only in hepatitis but also in healthy persons and sensitivity differences of PCR ...
Lens Concentration of Ofloxacin and Lomefloxacin in an Experimental Endophthalmitis Model
(Elsevier, 2007)
Background: Bacterial endophthalmitis is a serious complication of ocular surgery and penetrating trauma. The primary causative organisms are strains of Staphylococcus aureus and Staphylococcus epidermidis. Fluoroquinolones ...
Molecular Characterization Of Turkish Patients With Pyrimidine 5 ' Nucleotidase-I Deficiency
(Amer Soc Hematology, 2003)
Pyrimidine 5' nucleotidase-I (P5N-I) deficiency is a rare autosomal recessive disorder associated with hemolytic anemia, marked basophilic stippling, and accumulation of high concentrations of pyrimidine nucleotides within ...
Antimicrobial Resistance In Invasive Strains Of Escherichia Coli From Southern And Eastern Mediterranean Laboratories
(ESCMID, 2008)
From January 2003 to December 2005, 5091 susceptibility test results from invasive isolates of Escherichia coli, collected from blood cultures and cerebrospinal fluid routinely processed within 58 participating laboratories, ...
Molecular Investigation Of A Fungemia Outbreak Due To Candida Parapsilosis In An Intensive Care Unit
(Elsevier Brazil, 2008)
We investigated a nosocomial cluster of four Candida parapsilosis fungemia episodes that occurred in a neurological intensive care unit over a two-week period. The four infected patients had received parenteral nutrition ...
Congenital Isolated Adrenocorticotropin Deficiency: An Underestimated Cause Of Neonatal Death, Explained By Tpit Gene Mutations
(Endocrine Soc, 2005)
Tpit is a T box transcription factor important for terminal differentiation of pituitary proopiomelanocortin-expressing cells. We demonstrated that human and mouse mutations of the TPIT gene cause a neonatal-onset form of ...
Prevalence of Erm Genes Encoding Macrolide-Lincosamide-Streptogramin (Mls) Resistance Among Clinical Isolates of Staphylococcus Aureus in A Turkish University Hospital
(Blackwell Publishing, 2006)
This study investigated the prevalence of the erm(A), erm(B) and erm(C) genes among 122 MLS-resistant clinical isolates of Staphylococcus aureus from a Turkish university hospital. Of these isolates, 44 were inducibly ...
Rapid Determination of Rifampin Resistance in Clinical Isolates of Mycobacterium Tuberculosis by Real-Time Pcr
(Amer Soc Microbiology, 2005)
Real-time PCR was used to determine rifampin resistance in clinical isolates of Mycobacterium tuberculosis. Ninety-six rifampin-resistant isolates and 23 rifampin-susceptible isolates were included in the study. A 305-bp ...
Preliminary Evaluation of an Immunochromatographic Strip Test for Specific Treponema Pallidum Antibodies
(Amer Soc Microbiology, 2002)
We evaluated a prototype immunochromatographic strip (ICS) test for qualitative detection of Treponema pallidum antibodies in 353 sera from 157 patients. For sera from 43 syphilis patients, the ICSs were reactive, while ...
Plasma Glycine and Serine Levels in Schizophrenia Compared to Normal Controls and Major Depression: Relation to Negative Symptoms
(Oxford Univ Press, 2004)
Previous Studies have suggested decreased N-methyl-D-aspartate (NMDA)-type glutamate receptor function may contribute to increased negative symptoms in patients with schizophrenia. Consistent with this hypothesis, glycine, ...
Rapid Detection of Rifampin Resistance in Mycobacterium Tuberculosis Isolates by Heteroduplex Analysis and Determination of Rifamycin Cross-Resistance in Rifampin-Resistant Isolates
(Amer Soc Microbiology, 2003)
Direct heteroduplex analysis and a universal heteroduplex generator assay were performed to detect rifampin resistance rapidly in Turkish Mycobacterium tuberculosis isolates. Cross-resistance to rifapentine, rifabutin, and ...
Risk Factors For Breast Cancer In Turkish Women With Early Pregnancies And Long-Lasting Lactation - A Case-Control Study
(Taylor & Francis As, 2002)
A hospital-based case-control study was carried out among 504 women with breast cancer and 610 controls to analyse the risk factors for breast cancer in Turkey. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) ...
Methicillin-Resistant Staphylococcus Aureus Heterogeneously Resistant To Vancomycin In A Turkish University Hospital
(Oxford Univ Press, 2005)
Objectives: We investigated vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneously vancomycin-intermediate S. aureus (hetero-VISA) isolates from clinical specimens of hospitalized patients at Hacettepe ...
Mitochondrial Dna Analysis in The Turkish Leber'S Hereditary Optic Neuropathy Population
(Royal Coll Ophthalmologists, 2001)
Purpose To define the prevalence of a panel of mitochondrial DNA (mtDNA) mutations associated with Leber's hereditary optic neuropathy (LHON) in the Turkish LHON population. LHON-associated mtDNA mutations have been found ...
Mefv Mutations In Systemic Onset Juvenile Idiopathic Arthritis
(Oxford Univ Press, 2009)
Objectives. Autoinflammatory diseases constitute a large spectrum of monogenic diseases like FMF or cryopyrin-associated periodic
syndromes (CAPS) and complex genetic trait diseases such as systemic onset juvenile idiopathic ...
Hfe H63D Mutation Frequency Shows An Increase In Turkish Women With Breast Cancer
(BioMed Central, 2006)
Background The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular ...