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Endometrial Cancer Risk Prediction Including Serum-Based Biomarkers: Results From The Epic Cohort
(Wiley-Blackwell, 2017)
Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimina-tion. Adding biomarker data to these models may improve predictive capacity; to our knowledge, ...
Protective/Restorative Role of the Adipose Tissue-Derived Mesenchymal Stem Cells on the Radioiodine-Induced Salivary Gland Damage in Rats
(Assoc Radiology & Oncology, 2017)
Background. To analyze protective/regenerative effects of adipose tissue-derived mesenchymal stem cells (ADMSC) on I-131-Radioiodine (RAI)-induced salivary gland damage in rats. Materials and Methods. Study population ...
Acute Renal Failure Due To Small Cell Neuroendocrine Carcinoma Of The Left Kidney: A Case Report
(Spandidos Publ Ltd, 2017)
The majority of small cell carcinoma (SCC) cases originate from the lungs. SCC of the kidneys is rare. Among genitourinary tumors, renal cell carcinoma is the most common type of tumor to be associated with paraneoplastic ...
Treatment Of High-Risk Neuroblastoma: National Protocol Results Of The Turkish Pediatric Oncology Group
(Wolters Kluwer Medknow Publications, 2017)
Background: The national protocol aimed to improve the outcome of the high risk neuroblastoma patients by high-dose chemotherapy and stem cell rescue with intensive multimodal therapy. Materials and Methods: After the 6 ...
Gemcitabine Combined With The Monoclonal Antibody Nimotuzumab Is An Active First-Line Regimen In Kras Wildtype Patients With Locally Advanced Or Metastatic Pancreatic Cancer: A Multicenter, Randomized Phase Iib Study
(Oxford Univ Press, 2017)
Background: This randomized study was designed to investigate the superiority of gemcitabine (gem) plus nimotuzumab (nimo), an anti-epidermal growth factor receptor monoclonal antibody, compared with gem plus placebo as ...
Nivolumab For Relapsed Or Refractory Hodgkin Lymphoma: Real-Life Experience
(Oxford Univ Press, 2017)
Background: Reed-Sternberg cells of classical Hodgkin's lymphoma (cHL) are characterized by genetic alterations at the 9p24.1 locus, leading to over-expression of programmed death-ligand 1 and 2. In a phase 1b study, ...
Natural History Of T1N0M0 Hepatocellular Carcinoma: Large-Scale Study In The United States
(Karger, 2017)
Background: Hepatocellular carcinoma (HCC) prognosis depends on clinicopathological features in addition to the treatment provided. We aimed to assess the natural history of TNM stage I HCC tumors which received different ...
Adjuvant Small Pelvic Radiotherapy in Patients with Cervical Cancer Having Intermediate Risk Factors Only - Is It Sufficient?
(Karger, 2017)
Background: We sought to determine the outcomes of adjuvant small pelvic external beam radiotherapy (EBRT) and prognostic factors for survival and disease control. Patients and Methods: We retrospectively evaluated 113 ...
Reirradiation of Pediatric Tumors Using Hypofractionated Stereotactic Radiotherapy
(Sage Publications Inc, 2017)
Background: This study aimed to evaluate the efficacy and safety of hypofractionated stereotactic radiotherapy for reirradiation of recurrent pediatric tumors. Methods and Materials: The study included 23 pediatric patients ...
Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl
(Nature Publishing Group, 2017)
The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ...