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Pretransplant Mobilization With Granulocyte Colony-Stimulating Factor Improves B-Cell Reconstitution by Lentiviral Vector Gene Therapy In Scid-X1 Mice

Huston, Marshall W.; Riegman, Adriaan R. A.; Yadak, Rana; van Helsdingen, Yvette; de Boer, Helen; van Til, Niek P.; Wagemaker, Gerard (Mary Ann Liebert, Inc, 2014)

Hematopoietic stem cell (HSC) gene therapy is a demonstrated effective treatment for X-linked severe combined immunodeficiency (SCID-X1), but B-cell reconstitution and function has been deficient in many of the gene therapy ...