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Toplam kayıt 9, listelenen: 1-9
Investigation of 1377C/T Polymorphism of the Toll-Like Receptor 3 Among Patients with Chronic Hepatitis B
(Canadian Science Publishing, Nrc Research Press, 2016)
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis ...
Genes For Spinocerebellar Ataxia With Blindness And Deafness (Scabd/Scar3, Mim# 271250 And Scabd2)
(Nature Publishing Group, 2016)
Ataxia is a symptom that is often associated with syndromic inherited diseases. We previously reported the linkage of a novel syndrome, ataxia with blindness and deafness (SCAR3/SCABD, OMIM# 271250), to chromosome 6p21-p23 ...
Folate, Neopterin And Kynurenine Pathway In Patients With Statin Therapy
(Walter De Gruyter Gmbh, 2016)
Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes. ...
Impaired Amino Acid Transport At The Blood Brain Barrier Is A Cause Of Autism Spectrum Disorder
(Cell Press, 2016)
Autism spectrum disorders (ASD) are a group of genetic disorders often overlapping with other neurological conditions. We previously described abnormalities in the branched-chain amino acid (BCAA) catabolic pathway as a ...
Novel Triazolothiadiazines Act As Potent Anticancer Agents In Liver Cancer Cells Through Akt And Ask-1 Proteins
(Pergamon-Elsevier Science Ltd, 2016)
Newly designed triazolothiadiazines incorporating with structural motifs of nonsteroidal analgesic anti-inflammatory drugs were synthesized and screened for their bioactivity against epithelial cancer cells. Compounds with ...
Detection Of Neopterin In Tear Samples
(Walter De Gruyter Gmbh, 2016)
The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels. For this purpose, 20 systemically healthy volunteers ...
Supramolecular Gag-Like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration
(Amer Chemical Soc, 2016)
Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis. Here, we demonstrate supramolecular GAG-like ...
Ezrin Inhibition Up-Regulates Stress Response Gene Expression
(Amer Soc Biochemistry Molecular Biology Inc, 2016)
Ezrin is a member of the ERM (ezrin/radixin/moesin) family of proteins that links cortical cytoskeleton to the plasma membrane. High expression of ezrin correlates with poor prognosis and metastasis in osteosarcoma. In ...
Determination Of Rivaroxaban In Human Plasma By Solid-Phase Extraction-High Performance Liquid Chromatography
(Oxford Univ Press, 2016)
In this study, a solid-phase extraction (SPE)-high performance liquid chromatography (HPLC)-ultra violet (UV) method was developed for the determination of rivaroxaban (RIV), an oral anticoagulant drug, in human plasma ...