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Inherited And Acquired Immunodeficiencies Underlying Tuberculosis In Childhood
(Wiley, 2015)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb) and a few related mycobacteria, is a devastating disease, killing more than a million individuals per year worldwide. However, its pathogenesis remains largely ...
Functional Analysis Of Naturally Occurring Dclre1C Mutations And Correlation With The Clinical Phenotype Of Artemis Deficiency
(Mosby-Elsevier, 2015)
Background: The endonuclease ARTEMIS, which is encoded by the DCLRE1C gene, is a component of the nonhomologous end-joining pathway and participates in hairpin opening during the V(D)J recombination process and repair of ...
The Effect of Granulocyte Colony-Stimulating Factor on Immune-Modulatory Cytokines in the Bone Marrow Microenvironment and Mesenchymal Stem Cells of Healthy Donors
(Elsevier Science Inc, 2015)
Granulocyte colony stimulating factor (G-CSF) is sometimes administered to donors before bone marrow (BM) harvest. G-CSF primed (G-BM) and unprimed BM (U-BM) derived mesenchymal stem cells (MSC) were obtained from 16 healthy ...
Macvia-Aria Sentinel Network for Allergic Rhinitis (Mask-Rhinitis): The New Generation Guideline Implementation
(Wiley, 2015)
Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for ...
The Extended Clinical Phenotype of 64 Patients with Dedicator of Cytokinesis 8 Deficiency
(Mosby-Elsevier, 2015)
Background: Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE syndrome (HIES). Recognizing patients with CID/HIES is of clinical ...
Missed Opportunities For Hepatitis B Vaccination Among Diabetic Patients
(Taylor & Francis Inc, 2015)
Many infectious diseases in adults can be prevented by a life-long vaccination strategy'. Hepatitis B disease burden was shown to be higher in diabetic patients. American Advisory Committee on Immunization Practices ...
Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)
Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ...
Epidemiology And Outcome Of Fungemia In A Cancer Cohort Of The Infectious Diseases Group (Idg) Of The European Organization For Research And Treatment Of Cancer (Eortc 65031)
(Oxford Univ Press, 2015)
Background. Anti-cancer treatment and the cancer population have evolved since the last European Organisation for Research and Treatment of Cancer (EORTC) fungemia survey, and there are few recent large epidemiological ...