• Do All Hemolytic Anemias That Occur After Mitral Valve Repair Require Surgical Treatment? 

      Gungunes, Askin; Akpinar, Ibrahim; Dogan, Mehmet; Baser, Kazim; Yildirim, Ismail Safa; Haznedaroglu, Ibrahim C. (Wiley, 2010)
      We report on a 29-year-old woman with severe hemolytic anemia following mitral valve annuloplasty. Although hemolysis due to mechanical prosthetic mitral valve is well recognized, hemolytic anemia associated with mitral ...
    • Do ANCA-associated vasculitides and IgG4-related disease really overlap or not? 

      Erden, Abdulsamet; Bolek, Ertugrul Cagri; Yardimci, Kubra Gozde; Kilic, Levent; Bilgen, Sule Apras; Karadag, Omer (Wiley, 2019-09-30)
      Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and immunoglobulin G4-related disease (IgG4-RD) have some common features. The co-occurrence/concurrence of AAV and IgG4-RD was recently ...
    • Early Onset Collagen Vi Myopathies: Genetic and Clinical Correlations 

      Brinas, Laura; Richard, Pascale; Quijano-Roy, Susana; Gartioux, Corine; Ledeuil, Celine; Lacene, Emmanuelle; Makri, Samira; Ferreiro, Ana; Maugenre, Svetlana; Topaloglu, Haluk; Haliloglu, Goknur; Penisson-Besnier, Isabelle; Jeannet, Pierre-Yves; Merlini, Luciano; Navarro, Carmen; Toutain, Annick; Chaigne, Denys; Desguerre, Isabelle; de Die-Smulders, Christine; Dunand, Murielle; Echenne, Bernard; Eymard, Bruno; Kuntzer, Thierry; Maincent, Kim; Mayer, Michele; Plessis, Ghislaine; Rivier, Francois; Roelens, Filip; Stojkovic, Tanya; Lia Taratuto, Ana; Lubieniecki, Fabiana; Monges, Soledad; Tranchant, Christine; Viollet, Louis; Romero, Norma B.; Estournet, Brigitte; Guicheney, Pascale; Allamand, Valerie (Wiley, 2010)
      Objective: Mutations in the genes encoding the extracellular matrix protein collagen VI (ColVI) cause a spectrum of disorders with variable inheritance including Ullrich congenital muscular dystrophy, Bethlem myopathy, and ...
    • Effect of Neutrophil Apoptosis on Monocytic Cytokine Response to Porphyromonas Gingivalis Lipopolysaccharide 

      Berker, E; Kantarci, A; Hasturk, H; Van Dyke, TE (Wiley, 2005)
      Background: Neutrophil apoptosis may play a critical role in the resolution of inflammation by stimulating anti-inflammatory cytokine generation from monocytes. In this study, we investigated the effect of apoptotic ...
    • Efns Guidelines On Diagnosis And Treatment Of Primary Dystonias 

      Albanese, A.; Asmus, F.; Bhatia, K. P.; Elia, A. E.; Elibol, B.; Filippini, G.; Gasser, T.; Krauss, J. K.; Nardocci, N.; Newton, A.; Valls-Sole, J. (Wiley, 2011)
      Objectives: To provide a revised version of earlier guidelines published in 2006. Background: Primary dystonias are chronic and often disabling conditions with a widespread spectrum mainly in young people. Diagnosis: Primary ...
    • Electronic Clinical Decision Support System For Allergic Rhinitis Management: Mask E-Cdss 

      Courbis, Anne-Lise; Murray, Ruth Brigid; Arnavielhe, Sylvie; Caimmi, Davide; Bedbrook, Anna; Van Eerd, Michiel; De Vries, Govert; Dray, Gerard; Agache, Ioana; Morais-Almeida, Mario; Bachert, Claus; Bergmann, Karl Christian; Bosnic-Anticevich, Sinthia; Brozek, Jan; Bucca, Caterina; Camargos, Paulo; Canonica, Giorgio Walter; Carr, Warner; Casale, Thomas; Fonseca, Joao A.; Haahtela, Tari; Kalayci, Omer; Klimek, Ludger; Kuna, Piotr; Kvedariene, Violeta; Larenas Linnemann, Desiree; Lieberman, Phil; Mullol, Joaquim; Ohehir, Robyn; Papadopoulos, Nikolaos; Price, David; Ryan, Dermot; Samolinski, Boleslaw; Simons, F. Estelle; Tomazic, Peter; Triggiani, Massimo; Valiulis, Arunas; Valovirta, Erkka; Wagenmann, Martin; Wickman, Magnus; Yorgancioglu, Arzu; Bousquet, Jean (Wiley, 2018)
      Background: Allergic rhinitis (AR) management has changed in recent years following the switch from the concept of disease severity to the concept of disease control, publication of the AR clinical decision support system ...
    • Evidence For Regulation Of Udp-Glucuronosyltransferase (Ugt) 1A1 Protein Expression And Activity Via Dna Methylation In Healthy Human Livers 

      Yasar, Umit; Greenblatt, David J.; Guillemette, Chantal; Court, Michael H. (Wiley, 2013)
      Objectives Interindividual variability in glucuronidation of bilirubin and drugs by UDP-glucuronosyltransferase 1A1 (UGT1A1) is considerable and only partially explained by genetic polymorphisms and enzyme inducers. Here ...
    • Expanding The Phenotypic Spectrum Of Ecel1-Related Congenital Contracture Syndromes 

      Shaaban, S.; Duzcan, F.; Yildirim, C.; Chan, W. -M.; Andrews, C.; Akarsu, N. A.; Engle, E. C. (Wiley, 2014)
      Using a combination of homozygosity mapping and whole-exome sequencing (WES), we identified a novel missense c.1819G>A mutation (G607S) in the endothelin-converting enzyme-like 1 (ECEL1) gene in a consanguineous pedigree ...
    • Farnesylthiosalicylic Acid-Loaded Lipid-Polyethylene Glycol-Polymer Hybrid Nanoparticles For Treatment Of Glioblastoma 

      Kaffashi, Abbas; Lule, Sevda; Pehlivan, Sibel Bozdag; Sarisozen, Can; Vural, Imran; Kosucu, Husnu; Demir, Taner; Bugdayci, Kadir Emre; Soylemezoglu, Figen; Oguz, Kader Karli; Mut, Melike (Wiley, 2017)
      ObjectivesWe aimed to develop lipid-polyethylene glycol (PEG)-polymer hybrid nanoparticles, which have high affinity to tumour tissue with active ingredient, a new generation antineoplastic drug, farnesylthiosalicylic acid ...
    • Few Drugs Display Flip-Flop Pharmacokinetics And These Are Primarily Associated With Classes 3 And 4 Of The Bddcs 

      Garrison, Kimberly L.; Sahin, Selma; Benet, Leslie Z. (Wiley, 2015)
      This study was conducted to determine the number of drugs exhibiting flip-flop pharmacokinetics following oral (p.o.) dosing from immediate-release dosage forms and if they exhibit a common characteristic that may be ...
    • Financial Depth And The Asymmetric Impact Of Monetary Policy 

      Caglayan, Mustafa; Kocaaslan, Ozge Kandemir; Mouratidis, Kostas (Wiley, 2017)
      This paper investigates the importance of financial depth in evaluating the asymmetric impact of monetary policy on real output over the course of the US business cycle. We show that monetary policy has a significant impact ...
    • Focused Rf Hyperthermia Using Magnetic Fluids 

      Tasci, T. Onur; Vargel, Ibrahim; Arat, Anil; Guzel, Elif; Korkusuz, Petek; Atalar, Ergin (Wiley, 2009)
      Heat therapies such as hyperthermia and thermoablation are very promising approaches in the treatment of cancer. Compared with available hyperthermia modalities, magnetic fluid hyperthermia (MFH) yields better results in ...
    • Fragile Histidine Triad Protein, Ww Domain-Containing Oxidoreductase Protein Wwox, And Activator Protein 2 Gamma Expression Levels Correlate With Basal Phenotype In Breast Cancer 

      Guler, Gulnur; Huebner, Kay; Himmetoglu, Cigdem; Jimenez, Rafael E.; Costinean, Stefan; Volinia, Stefano; Pilarski, Robert T.; Hayran, Mutlu; Shapiro, Charles L. (Wiley, 2009)
      BACKGROUND: The expression of fragile histidine triad protein (Fhit) and WW domain-containing oxidor-eductase protein (Wwox), tumor suppressors that are encoded by fragile (FRA) loci FRA3B and FPA16D, are lost concordantly ...
    • Functional Exhaustion Of Cd4(+) T Cells Induced By Co-Stimulatory Signals From Myeloid Leukaemia Cells 

      Ozkazanc, Didem; Yoyen-Ermis, Digdem; Tavukcuoglu, Ece; Buyukasik, Yahya; Esendagli, Gunes (Wiley, 2016)
      To cope with immune responses, tumour cells implement elaborate strategies such as adaptive resistance and induction of T-cell exhaustion. T-cell exhaustion has been identified as a state of hyporesponsiveness that arises ...
    • Genotype-Phenotype Analysis Of Human Frontoparietal Polymicrogyria Syndromes 

      Piao, XH; Chang, BS; Bodell, A; Woods, K; BenZeev, B; Topcu, M; Guerrini, R; Goldberg-Stern, H; Sztriha, L; Dobyns, WB; Barkovich, AJ; Walsh, CA (Wiley, 2005)
      Human cerebral cortical polymicrogyria is a heterogeneous disorder, with only one known gene (GPR56) associated with an apparently distinctive phenotype, termed bilateral frontoparietal polymicrogyria (BFPP). To define the ...
    • Global Analysis Of Satellite Tracking Data Shows That Adult Green Turtles Are Significantly Aggregated In Marine Protected Areas 

      Scott, Rebecca; Hodgson, David J.; Witt, Matthew J.; Coyne, Michael S.; Adnyana, Windia; Blumenthal, Janice M.; Broderick, Annette C.; Canbolat, Ali Fuat; Catry, Paulo; Ciccione, Stephane; Delcroix, Eric; Hitipeuw, Creusa; Luschi, Paolo; Pet-Soede, L.; Pendoley, Kellie; Richardson, Peter B.; Rees, Alan F.; Godley, Brendan J. (Wiley, 2012)
      Aim Tracking technologies are often proposed as a method to elucidate the complex migratory life histories of migratory marine vertebrates, allowing spatially explicit threats to be identified and mitigated. We conducted ...
    • Homozygous Indel Mutation In Cdh11 As The Probable Cause Of Elsahy-Waters Syndrome 

      Taskiran, Ekim Z.; Karaosmanoglu, Beren; Kosukcu, Can; Dogan, Ozlem A.; Taylan-Sekeroglu, Hande; Simsek-Kiper, Pelin O.; Utine, Eda G.; Boduroglu, Koray; Alikasifoglu, Mehmet (Wiley, 2017)
      Two sisters from a consanguineous couple were seen in genetics department for facial dysmorphic features and glaucoma. They both had broad foreheads, hypertelorism, megalocorneas, thick eyebrows with synophrys, flat malar ...
    • Hyperacute Graft-vs.-Host Disease After Related HLA-Identical Umbilical Cord Blood Transplantation 

      Kuskonmaz, Baris; Gocer, Safak; Ersoy-Ewans, Sibel; Cetin Ozman, Fatma; Cetin, Mualla (Wiley, 2007)
      haGVHD has been described following bone marrow and peripheral blood stem cell transplantation and in a single case who received unrelated HLA mismatched CB. An unusual case of haGVHD following HLA 6/6-matched sibling CBT ...
    • Identification Of Susceptibility Loci In Il6, Rps9/Lilrb3, And An Intergenic Locus On Chromosome 21Q22 In Takayasu Arteritis In A Genome-Wide Association Study 

      Renauer, Paul A.; Saruhan-Direskeneli, Guher; Coit, Patrick; Adler, Adam; Aksu, Kenan; Keser, Gokhan; Alibaz-Oner, Fatma; Aydin, Sibel Z.; Kamali, Sevil; Inanc, Murat; Carette, Simon; Cuthbertson, David; Hoffman, Gary S.; Akar, Servet; Onen, Fatos; Akkoc, Nurullah; Khalidi, Nader A.; Koening, Curry; Karadag, Omer; Kiraz, Sedat; Langford, Carol A.; Maksimowicz-McKinnon, Kathleen; McAlear, Carol A.; Ozbalkan, Zeynep; Ates, Askin; Karaaslan, Yasar; Duzgun, Nursen; Monach, Paul A.; Ozer, Huseyin T. E.; Erken, Eren; Ozturk, Mehmet A.; Yazici, Ayten; Cefle, Ayse; Onat, Ahmet Mesut; Kisacik, Bunyamin; Pagnoux, Christian; Kasifoglu, Timucin; Seyahi, Emire; Fresko, Izzet; Seo, Philip; Sreih, Antoine G.; Warrington, Kenneth J.; Ytterberg, Steven R.; Cobankara, Veli; Cunninghame-Graham, Deborah S.; Vyse, Timothy J.; Pamuk, Omer N.; Tunc, S. Ercan; Dalkilic, Ediz; Bicakcigil, Muge; Yentur, Sibel P.; Wren, Jonathan D.; Merkel, Peter A.; Direskeneli, Haner; Sawalha, Amr H. (Wiley, 2015)
      Objective. Takayasu arteritis is a rare large vessel vasculitis with incompletely understood etiology. This study was undertaken to perform the first unbiased genome-wide association analysis of Takayasu arteritis. Methods. ...
    • IL-12Rβ1 Deficiency: Mutation Update and Description of the IL12RB1 Variation Database 

      van de Vosse, Esther; Haverkamp, Margje H.; Ramirez-Alejo, Noe; Martinez-Gallo, Monica; Blancas-Galicia, Lizbeth; Metin, Ayse; Garty, Ben Zion; Sun-Tan, Cagman; Broides, Arnon; de Paus, Roelof A.; Keskin, Ozlem; Cagdas, Deniz; Tezcan, Ilhan; Lopez-Ruzafa, Encarna; Arostegui, Juan I.; Levy, Jacov; Espinosa-Rosales, Francisco J.; Sanal, Ozden; Santos-Argumedo, Leopoldo; Casanova, Jean-Laurent; Boisson-Dupuis, Stephanie; van Dissel, Jaap T.; Bustamante, Jacinta (Wiley, 2013)
      IL-12R1 deficiency is an autosomal recessive disorder characterized by predisposition to recurrent and/or severe infections caused by otherwise poorly pathogenic mycobacteria and salmonella. IL-12R1 is a receptor chain of ...